ELOVL2-AS1

Summary

ELOVL2-AS1 (ELOVL2 antisense RNA 1, HGNC:44156) is a long non-coding RNA gene on chromosome 6p24.2.

Predicted to be involved in RNA processing. Predicted to be located in nucleolus.

Source: NCBI Gene 100506409 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44156
Approved symbol	ELOVL2-AS1
Name	ELOVL2 antisense RNA 1
Location	6p24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230314
Ensembl biotype	lncRNA
Entrez	100506409
RNAcentral	URS000075AE0D — lncRNA, 1823 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000456190, ENST00000456616, ENST00000606532, ENST00000607275, ENST00000657744, ENST00000661751, ENST00000666965, ENST00000667154, ENST00000667435, ENST00000762557, ENST00000762558

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456190 — 5 exons

Exon	Start	End
ENSE00001638322	11077689	11079151
ENSE00001672075	11047909	11047999
ENSE00001673708	11073455	11073545
ENSE00001680018	11049109	11049219
ENSE00001713879	11043760	11043825

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 85.93.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0207 / max 6.7663, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
65786	0.0129	4
65787	0.0078	3

Top tissues by expression

207 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.93	gold quality
colonic epithelium	UBERON:0000397	83.16	gold quality
right testis	UBERON:0004534	81.58	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.86	gold quality
left testis	UBERON:0004533	79.76	gold quality
buccal mucosa cell	CL:0002336	79.10	silver quality
testis	UBERON:0000473	79.03	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.79	gold quality
ventricular zone	UBERON:0003053	70.81	gold quality
spinal cord	UBERON:0002240	70.06	gold quality
cortical plate	UBERON:0005343	68.31	gold quality
adult organism	UBERON:0007023	68.16	gold quality
bone marrow cell	CL:0002092	67.11	silver quality
ganglionic eminence	UBERON:0004023	66.36	gold quality
nucleus accumbens	UBERON:0001882	66.19	gold quality
caudate nucleus	UBERON:0001873	65.67	gold quality
sperm	CL:0000019	64.44	gold quality
putamen	UBERON:0001874	64.39	gold quality
amygdala	UBERON:0001876	63.68	gold quality
anterior cingulate cortex	UBERON:0009835	62.44	gold quality
ileal mucosa	UBERON:0000331	61.82	silver quality
tibialis anterior	UBERON:0001385	60.95	silver quality
hypothalamus	UBERON:0001898	60.52	gold quality
right frontal lobe	UBERON:0002810	60.09	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.98	gold quality
substantia nigra	UBERON:0002038	59.91	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	59.78	gold quality
right lobe of liver	UBERON:0001114	58.17	gold quality
pigmented layer of retina	UBERON:0001782	58.16	silver quality
midbrain	UBERON:0001891	57.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.44

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• ELOVL2-AS1 inhibits migration of triple negative breast cancer. (PMID:35441059)
• ELOVL2-AS1 suppresses tamoxifen resistance by sponging miR-1233-3p in breast cancer. (PMID:37908128)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.