EMC1-AS1

Summary

EMC1-AS1 (EMC1 antisense RNA 1, HGNC:54050) is a long non-coding RNA gene on chromosome 1p36.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54050
Approved symbol	EMC1-AS1
Name	EMC1 antisense RNA 1
Location	1p36.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230424
Ensembl biotype	lncRNA
Entrez	101927895
RNAcentral	URS0000A77184 — lncRNA, 639 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000437898, ENST00000690421, ENST00000842450, ENST00000842451, ENST00000842452, ENST00000842453

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000437898 — 2 exons

Exon	Start	End
ENSE00003987868	19240257	19240709
ENSE00004267614	19210330	19210559

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 85.17.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 7.1868 / max 748.0319, expressed in 1648 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
1052	4.0204	1291
1053	2.2917	994
1051	0.8747	501

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.17	gold quality
islet of Langerhans	UBERON:0000006	80.20	gold quality
ventricular zone	UBERON:0003053	77.64	gold quality
monocyte	CL:0000576	76.24	gold quality
right atrium auricular region	UBERON:0006631	76.19	gold quality
leukocyte	CL:0000738	76.02	gold quality
left ovary	UBERON:0002119	75.86	gold quality
apex of heart	UBERON:0002098	75.84	gold quality
heart left ventricle	UBERON:0002084	75.76	gold quality
ovary	UBERON:0000992	75.49	gold quality
gall bladder	UBERON:0002110	75.38	gold quality
heart	UBERON:0000948	75.16	gold quality
bone marrow	UBERON:0002371	75.15	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	74.92	gold quality
substantia nigra	UBERON:0002038	74.82	gold quality
ganglionic eminence	UBERON:0004023	74.67	gold quality
bone marrow cell	CL:0002092	74.18	gold quality
pancreas	UBERON:0001264	74.14	gold quality
fallopian tube	UBERON:0003889	74.11	gold quality
gastrocnemius	UBERON:0001388	74.09	gold quality
right ovary	UBERON:0002118	74.06	gold quality
muscle of leg	UBERON:0001383	73.99	gold quality
lymph node	UBERON:0000029	73.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	73.68	gold quality
omental fat pad	UBERON:0010414	73.63	gold quality
adipose tissue	UBERON:0001013	73.16	gold quality
left adrenal gland cortex	UBERON:0035825	73.00	gold quality
lower esophagus muscularis layer	UBERON:0035833	72.93	gold quality
muscle tissue	UBERON:0002385	72.86	gold quality
lower esophagus	UBERON:0013473	72.85	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.