EMC3-AS1

Summary

EMC3-AS1 (EMC3 antisense RNA 1, HGNC:49223) is a unprocessed pseudogene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49223
Approved symbol	EMC3-AS1
Name	EMC3 antisense RNA 1
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000180385
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	442075
RNAcentral	URS000075996B — lncRNA, 4696 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000438698

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438698 — 5 exons

Exon	Start	End
ENSE00001649002	9988372	9988477
ENSE00001663016	9988712	9988748
ENSE00001728438	9992869	9993011
ENSE00001781238	9987904	9988007
ENSE00001784632	9994188	9994331

Expression profiles

Bgee: expression breadth ubiquitous, 192 present calls, max score 84.04.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0173 / max 16.4304, expressed in 597 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
35265	1.0173	597

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	84.04	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.54	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.68	gold quality
trabecular bone tissue	UBERON:0002483	81.45	gold quality
secondary oocyte	CL:0000655	80.72	gold quality
oocyte	CL:0000023	80.36	gold quality
cardiac muscle of right atrium	UBERON:0003379	78.31	gold quality
left ventricle myocardium	UBERON:0006566	78.28	gold quality
colonic epithelium	UBERON:0000397	77.99	gold quality
sural nerve	UBERON:0015488	76.97	gold quality
tendon of biceps brachii	UBERON:0008188	76.40	silver quality
tendon	UBERON:0000043	75.25	gold quality
bone marrow	UBERON:0002371	74.89	gold quality
lower esophagus mucosa	UBERON:0035834	74.85	gold quality
calcaneal tendon	UBERON:0003701	74.58	gold quality
left ovary	UBERON:0002119	74.25	gold quality
mucosa of stomach	UBERON:0001199	74.14	gold quality
right ovary	UBERON:0002118	73.89	gold quality
lymph node	UBERON:0000029	73.67	gold quality
stromal cell of endometrium	CL:0002255	73.48	gold quality
cerebellar hemisphere	UBERON:0002245	73.37	gold quality
cerebellar cortex	UBERON:0002129	73.24	gold quality
ganglionic eminence	UBERON:0004023	73.19	gold quality
nasal cavity epithelium	UBERON:0005384	73.11	silver quality
ventricular zone	UBERON:0003053	73.07	gold quality
Brodmann (1909) area 23	UBERON:0013554	73.02	silver quality
uterine cervix	UBERON:0000002	72.85	gold quality
cerebellum	UBERON:0002037	72.63	gold quality
bone marrow cell	CL:0002092	72.58	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.52	gold quality

Single-cell (SCXA)

Detected in 3 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-ENAD-21	yes	719.95
E-CURD-7	yes	718.62
E-ANND-3	no	2.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.