EML2-AS1

Summary

EML2-AS1 (EML2 antisense RNA 1, HGNC:48331) is a long non-coding RNA gene on chromosome 19q13.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48331
Approved symbol	EML2-AS1
Name	EML2 antisense RNA 1
Location	19q13.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000267757
Ensembl biotype	lncRNA
Entrez	100287177
RNAcentral	URS00008121FA — lncRNA, 1093 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 3 lncRNA, 1 retained_intron

ENST00000587092, ENST00000591087, ENST00000623430, ENST00000785827

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000587092 — 2 exons

Exon	Start	End
ENSE00002742445	45641879	45642357
ENSE00002763020	45641647	45641766

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 91.42.

FANTOM5 (CAGE): breadth broad, TPM avg 1.8810 / max 89.2067, expressed in 697 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
176500	1.5684	624
176499	0.2220	98
176498	0.0905	37

Top tissues by expression

222 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
kidney epithelium	UBERON:0004819	91.42	gold quality
left ventricle myocardium	UBERON:0006566	91.09	gold quality
cardiac muscle of right atrium	UBERON:0003379	89.78	gold quality
nasal cavity epithelium	UBERON:0005384	89.68	gold quality
upper arm skin	UBERON:0004263	88.70	gold quality
vena cava	UBERON:0004087	87.73	silver quality
epithelial cell of pancreas	CL:0000083	86.89	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	86.23	gold quality
cerebellar vermis	UBERON:0004720	86.16	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	85.36	gold quality
myocardium	UBERON:0002349	85.24	gold quality
pericardium	UBERON:0002407	83.24	silver quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	83.08	gold quality
lateral nuclear group of thalamus	UBERON:0002736	82.49	gold quality
pons	UBERON:0000988	81.79	silver quality
pylorus	UBERON:0001166	81.13	gold quality
trachea	UBERON:0003126	81.12	gold quality
saphenous vein	UBERON:0007318	81.04	gold quality
inferior vagus X ganglion	UBERON:0005363	80.62	gold quality
ventral tegmental area	UBERON:0002691	80.57	gold quality
lateral globus pallidus	UBERON:0002476	80.46	gold quality
superior surface of tongue	UBERON:0007371	80.44	silver quality
substantia nigra pars compacta	UBERON:0001965	79.76	gold quality
buccal mucosa cell	CL:0002336	79.68	silver quality
layer of synovial tissue	UBERON:0007616	79.59	gold quality
substantia nigra pars reticulata	UBERON:0001966	79.46	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.05	gold quality
superior vestibular nucleus	UBERON:0007227	78.79	gold quality
parotid gland	UBERON:0001831	78.57	gold quality
thymus	UBERON:0002370	78.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.35

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.