EN2-DT

Summary

EN2-DT (EN2 divergent transcript, HGNC:55659) is a long non-coding RNA gene on chromosome 7q36.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55659
Approved symbol	EN2-DT
Name	EN2 divergent transcript
Location	7q36.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236544
Ensembl biotype	lncRNA
Entrez	121832807
RNAcentral	URS0000D56EE3 — lncRNA, 553 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000419225, ENST00000781270, ENST00000781271, ENST00000781272, ENST00000781273

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000419225 — 3 exons

Exon	Start	End
ENSE00001612893	155456990	155457099
ENSE00001674931	155451167	155451322
ENSE00001679785	155421206	155421473

Expression profiles

Bgee: expression breadth broad, 45 present calls, max score 72.69.

Top tissues by expression

45 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	72.69	gold quality
cerebellar hemisphere	UBERON:0002245	72.64	gold quality
cerebellar cortex	UBERON:0002129	72.39	gold quality
cerebellum	UBERON:0002037	72.27	gold quality
sural nerve	UBERON:0015488	71.64	gold quality
hypothalamus	UBERON:0001898	59.00	gold quality
substantia nigra	UBERON:0002038	58.89	gold quality
cortex of kidney	UBERON:0001225	54.87	gold quality
tibial nerve	UBERON:0001323	54.58	gold quality
monocyte	CL:0000576	54.46	gold quality
right frontal lobe	UBERON:0002810	52.91	gold quality
prefrontal cortex	UBERON:0000451	50.29	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.70	gold quality
gastrocnemius	UBERON:0001388	48.59	silver quality
blood	UBERON:0000178	46.85	silver quality
primary visual cortex	UBERON:0002436	46.71	silver quality
skin of abdomen	UBERON:0001416	45.68	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.58	gold quality
thoracic mammary gland	UBERON:0005200	45.22	gold quality
zone of skin	UBERON:0000014	45.09	gold quality
vagina	UBERON:0000996	44.96	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	44.87	gold quality
skin of leg	UBERON:0001511	44.10	gold quality
body of pancreas	UBERON:0001150	43.72	silver quality
heart left ventricle	UBERON:0002084	43.54	silver quality
subcutaneous adipose tissue	UBERON:0002190	43.41	gold quality
right adrenal gland	UBERON:0001233	42.27	silver quality
putamen	UBERON:0001874	42.15	silver quality
muscle layer of sigmoid colon	UBERON:0035805	40.78	silver quality
body of stomach	UBERON:0001161	40.73	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.52

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.