ENAM-AS1

Summary

ENAM-AS1 (ENAM and JCHAIN antisense RNA 1, HGNC:58806) is a long non-coding RNA gene on chromosome 4q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58806
Approved symbol	ENAM-AS1
Name	ENAM and JCHAIN antisense RNA 1
Location	4q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000286848
Ensembl biotype	lncRNA
Entrez	101927297

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000472903, ENST00000509221, ENST00000779448

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000472903 — 4 exons

Exon	Start	End
ENSE00001816881	70681499	70681599
ENSE00001818508	70662129	70662223
ENSE00001826374	70686607	70686816
ENSE00001885831	70637745	70637843

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 89.50.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	89.50	gold quality
duodenum	UBERON:0002114	84.56	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.57	silver quality
rectum	UBERON:0001052	83.51	gold quality
bone marrow cell	CL:0002092	80.18	gold quality
lymph node	UBERON:0000029	74.17	gold quality
mucosa of transverse colon	UBERON:0004991	73.27	gold quality
muscle tissue	UBERON:0002385	71.68	gold quality
bone marrow	UBERON:0002371	71.46	gold quality
smooth muscle tissue	UBERON:0001135	70.92	gold quality
tonsil	UBERON:0002372	69.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.09	gold quality
gall bladder	UBERON:0002110	67.92	gold quality
small intestine	UBERON:0002108	67.58	gold quality
intestine	UBERON:0000160	67.06	gold quality
transverse colon	UBERON:0001157	66.75	gold quality
skeletal muscle tissue	UBERON:0001134	66.71	gold quality
vermiform appendix	UBERON:0001154	66.48	gold quality
colon	UBERON:0001155	66.40	gold quality
small intestine Peyer’s patch	UBERON:0003454	65.84	gold quality
monocyte	CL:0000576	65.61	gold quality
leukocyte	CL:0000738	65.52	gold quality
saliva-secreting gland	UBERON:0001044	65.52	gold quality
minor salivary gland	UBERON:0001830	64.62	gold quality
spleen	UBERON:0002106	64.01	gold quality
urinary bladder	UBERON:0001255	61.42	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.17	gold quality
blood	UBERON:0000178	60.18	gold quality
islet of Langerhans	UBERON:0000006	59.76	gold quality
fundus of stomach	UBERON:0001160	59.62	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	21410.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.