EPCAM-DT

Summary

EPCAM-DT (EPCAM divergent transcript, HGNC:52639) is a long non-coding RNA gene on chromosome 2p21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52639
Approved symbol	EPCAM-DT
Name	EPCAM divergent transcript
Location	2p21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234690
Ensembl biotype	lncRNA
Entrez	101927043
RNAcentral	URS000075DB28 — lncRNA, 923 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000413185, ENST00000419035, ENST00000441997, ENST00000448713, ENST00000450550, ENST00000658129, ENST00000781953, ENST00000781954, ENST00000781955, ENST00000781956, ENST00000781957, ENST00000781958

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413185 — 4 exons

Exon	Start	End
ENSE00001682041	47332934	47333026
ENSE00001800169	47332273	47332408
ENSE00004154523	47331363	47332107
ENSE00004154527	47344901	47345112

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 83.18.

FANTOM5 (CAGE): breadth broad, TPM avg 2.0271 / max 108.5483, expressed in 574 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
28226	0.8125	355
28228	0.6215	287
28227	0.3867	197
28225	0.1715	55
28224	0.0217	12
28223	0.0132	7

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of transverse colon	UBERON:0004991	83.18	gold quality
ganglionic eminence	UBERON:0004023	82.89	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.49	silver quality
ventricular zone	UBERON:0003053	78.75	gold quality
right uterine tube	UBERON:0001302	78.02	gold quality
rectum	UBERON:0001052	76.79	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	75.32	gold quality
colonic epithelium	UBERON:0000397	74.96	gold quality
cortical plate	UBERON:0005343	73.58	gold quality
islet of Langerhans	UBERON:0000006	73.32	gold quality
spinal cord	UBERON:0002240	72.16	gold quality
buccal mucosa cell	CL:0002336	71.82	silver quality
transverse colon	UBERON:0001157	71.03	gold quality
adenohypophysis	UBERON:0002196	70.08	gold quality
pancreas	UBERON:0001264	69.54	gold quality
body of pancreas	UBERON:0001150	68.65	gold quality
pituitary gland	UBERON:0000007	68.51	gold quality
cerebellar hemisphere	UBERON:0002245	68.04	gold quality
minor salivary gland	UBERON:0001830	68.03	gold quality
cerebellar cortex	UBERON:0002129	67.97	gold quality
small intestine Peyer’s patch	UBERON:0003454	67.80	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.80	gold quality
right adrenal gland cortex	UBERON:0035827	67.39	gold quality
endocervix	UBERON:0000458	67.34	gold quality
small intestine	UBERON:0002108	66.20	gold quality
left ovary	UBERON:0002119	66.18	gold quality
cerebellum	UBERON:0002037	66.13	gold quality
adult mammalian kidney	UBERON:0000082	65.98	gold quality
metanephros cortex	UBERON:0010533	65.53	gold quality
gall bladder	UBERON:0002110	65.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.