EPHA1-AS1

Summary

EPHA1-AS1 (EPHA1 antisense RNA 1, HGNC:27799) is a long non-coding RNA gene on chromosome 7q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27799
Approved symbol	EPHA1-AS1
Name	EPHA1 antisense RNA 1
Location	7q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000229153
Ensembl biotype	lncRNA
Entrez	285965
RNAcentral	URS000075E553 — lncRNA, 5034 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 43 — 43 lncRNA

ENST00000421648, ENST00000429289, ENST00000690912, ENST00000692812, ENST00000703017, ENST00000841052, ENST00000841053, ENST00000841054, ENST00000841055, ENST00000841056, ENST00000841057, ENST00000841058, ENST00000841059, ENST00000841060, ENST00000841061, ENST00000841062, ENST00000841063, ENST00000841064, ENST00000841065, ENST00000841066, ENST00000841067, ENST00000841068, ENST00000841069, ENST00000841070, ENST00000841071, ENST00000841072, ENST00000841073, ENST00000841074, ENST00000841075, ENST00000841076, ENST00000841077, ENST00000841078, ENST00000841079, ENST00000841080, ENST00000841081, ENST00000841082, ENST00000841083, ENST00000841084, ENST00000841085, ENST00000841086, ENST00000841087, ENST00000841088, ENST00000841089

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421648 — 3 exons

Exon	Start	End
ENSE00001788748	143415068	143415199
ENSE00004265038	143407562	143407890
ENSE00004265055	143415537	143415840

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 79.25.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1813 / max 12.5526, expressed in 68 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
81797	0.1813	68

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	79.25	gold quality
leukocyte	CL:0000738	78.47	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.27	gold quality
bone marrow cell	CL:0002092	74.68	gold quality
blood	UBERON:0000178	71.40	gold quality
bone marrow	UBERON:0002371	70.58	gold quality
vermiform appendix	UBERON:0001154	67.27	gold quality
colonic epithelium	UBERON:0000397	66.98	silver quality
lower esophagus mucosa	UBERON:0035834	66.61	gold quality
tonsil	UBERON:0002372	65.11	gold quality
descending thoracic aorta	UBERON:0002345	64.95	gold quality
lymph node	UBERON:0000029	64.72	gold quality
mucosa of stomach	UBERON:0001199	64.50	gold quality
skeletal muscle tissue	UBERON:0001134	64.06	gold quality
tibial artery	UBERON:0007610	64.04	gold quality
popliteal artery	UBERON:0002250	64.02	gold quality
placenta	UBERON:0001987	63.07	gold quality
granulocyte	CL:0000094	62.62	gold quality
esophagus mucosa	UBERON:0002469	62.45	gold quality
calcaneal tendon	UBERON:0003701	62.40	gold quality
thoracic aorta	UBERON:0001515	61.06	gold quality
ascending aorta	UBERON:0001496	60.90	gold quality
right lung	UBERON:0002167	60.76	gold quality
right coronary artery	UBERON:0001625	60.18	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.18	gold quality
lung	UBERON:0002048	59.55	gold quality
esophagus	UBERON:0001043	59.15	gold quality
upper lobe of left lung	UBERON:0008952	58.70	gold quality
gall bladder	UBERON:0002110	58.46	gold quality
fundus of stomach	UBERON:0001160	58.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.36

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.