EPHA2-AS1

Summary

EPHA2-AS1 (EPHA2 antisense RNA 1, HGNC:40216) is a long non-coding RNA gene on chromosome 1p36.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40216
Approved symbol	EPHA2-AS1
Name	EPHA2 antisense RNA 1
Location	1p36.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227959
Ensembl biotype	lncRNA
Entrez	101927479
RNAcentral	URS00026A266E — lncRNA, 2143 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000424774, ENST00000426353, ENST00000793379, ENST00000793381, ENST00000793382, ENST00000793383, ENST00000793384, ENST00000793385, ENST00000793386

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000424774 — 2 exons

Exon	Start	End
ENSE00001597546	16156971	16158148
ENSE00004176236	16155072	16155755

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 77.37.

Top tissues by expression

226 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	77.37	gold quality
lower esophagus mucosa	UBERON:0035834	73.04	gold quality
esophagus mucosa	UBERON:0002469	68.83	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.92	gold quality
minor salivary gland	UBERON:0001830	63.34	gold quality
sural nerve	UBERON:0015488	62.84	silver quality
mucosa of transverse colon	UBERON:0004991	61.39	gold quality
colonic epithelium	UBERON:0000397	61.19	silver quality
vagina	UBERON:0000996	61.06	gold quality
mouth mucosa	UBERON:0003729	60.93	gold quality
saliva-secreting gland	UBERON:0001044	60.66	gold quality
ventricular zone	UBERON:0003053	60.42	gold quality
metanephros cortex	UBERON:0010533	60.02	gold quality
esophagus	UBERON:0001043	59.83	gold quality
ectocervix	UBERON:0012249	59.59	gold quality
small intestine Peyer’s patch	UBERON:0003454	58.16	gold quality
stromal cell of endometrium	CL:0002255	58.11	gold quality
uterine cervix	UBERON:0000002	58.03	gold quality
skin of abdomen	UBERON:0001416	57.76	gold quality
small intestine	UBERON:0002108	57.59	gold quality
skin of leg	UBERON:0001511	57.51	gold quality
transverse colon	UBERON:0001157	57.21	gold quality
islet of Langerhans	UBERON:0000006	56.05	gold quality
tonsil	UBERON:0002372	55.92	gold quality
zone of skin	UBERON:0000014	55.65	gold quality
mucosa of stomach	UBERON:0001199	55.56	gold quality
body of stomach	UBERON:0001161	55.39	gold quality
body of uterus	UBERON:0009853	54.93	gold quality
pancreas	UBERON:0001264	54.66	gold quality
stomach	UBERON:0000945	54.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.88

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.