EPHA5-AS1

Summary

EPHA5-AS1 (EPHA5 antisense RNA 1, HGNC:50602) is a long non-coding RNA gene on chromosome 4q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:50602
Approved symbol	EPHA5-AS1
Name	EPHA5 antisense RNA 1
Location	4q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250846
Ensembl biotype	lncRNA
Entrez	100144602
RNAcentral	URS000075EA19 — lncRNA, 1198 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000503625, ENST00000507117, ENST00000509473, ENST00000514260, ENST00000782717, ENST00000782718

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503625 — 4 exons

Exon	Start	End
ENSE00002040051	65702178	65702345
ENSE00002076899	65705313	65708352
ENSE00004026295	65670617	65670673
ENSE00004026296	65697949	65698031

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 90.64.

FANTOM5 (CAGE): breadth broad, TPM avg 1.2496 / max 56.2602, expressed in 341 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
47803	0.9055	296
47802	0.2090	102
47801	0.1352	62

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left ventricle myocardium	UBERON:0006566	90.64	gold quality
cardiac muscle of right atrium	UBERON:0003379	90.58	gold quality
kidney epithelium	UBERON:0004819	87.32	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.66	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.88	gold quality
ganglionic eminence	UBERON:0004023	81.03	gold quality
ventricular zone	UBERON:0003053	78.88	gold quality
monocyte	CL:0000576	78.08	gold quality
nasal cavity epithelium	UBERON:0005384	77.81	gold quality
myocardium	UBERON:0002349	77.77	gold quality
vastus lateralis	UBERON:0001379	77.18	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	76.59	gold quality
quadriceps femoris	UBERON:0001377	76.26	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	73.73	gold quality
superficial temporal artery	UBERON:0001614	73.19	gold quality
muscle tissue	UBERON:0002385	72.97	gold quality
cortical plate	UBERON:0005343	72.38	gold quality
buccal mucosa cell	CL:0002336	72.09	silver quality
skeletal muscle tissue	UBERON:0001134	71.47	gold quality
adrenal tissue	UBERON:0018303	71.45	gold quality
sural nerve	UBERON:0015488	70.45	gold quality
adenohypophysis	UBERON:0002196	70.40	gold quality
heart right ventricle	UBERON:0002080	70.02	gold quality
pituitary gland	UBERON:0000007	70.00	gold quality
biceps brachii	UBERON:0001507	69.58	gold quality
hypothalamus	UBERON:0001898	68.80	gold quality
epithelial cell of pancreas	CL:0000083	68.65	gold quality
prefrontal cortex	UBERON:0000451	68.20	gold quality
anterior cingulate cortex	UBERON:0009835	68.01	gold quality
left lobe of thyroid gland	UBERON:0001120	67.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.