EPM2A-DT

Summary

EPM2A-DT (EPM2A divergent transcript, HGNC:48990) is a long non-coding RNA gene on chromosome 6q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48990
Approved symbol	EPM2A-DT
Name	EPM2A divergent transcript
Location	6q24.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235652
Ensembl biotype	lncRNA
Entrez	100507557
RNAcentral	URS000075F0E0 — lncRNA, 4103 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 28 — 28 lncRNA

ENST00000452617, ENST00000587426, ENST00000587540, ENST00000591489, ENST00000592775, ENST00000606388, ENST00000626833, ENST00000626919, ENST00000627375, ENST00000629681, ENST00000630041, ENST00000630919, ENST00000653352, ENST00000654828, ENST00000658327, ENST00000660586, ENST00000663890, ENST00000688715, ENST00000690526, ENST00000691670, ENST00000700853, ENST00000805026, ENST00000805027, ENST00000805028, ENST00000805029, ENST00000805030, ENST00000805031, ENST00000805032

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000452617 — 4 exons

Exon	Start	End
ENSE00001621764	145881579	145881648
ENSE00001685496	145828361	145828456
ENSE00004196894	145814858	145815431
ENSE00004196899	145883205	145885835

Expression profiles

Bgee: expression breadth ubiquitous, 217 present calls, max score 92.95.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.7811 / max 54.2742, expressed in 1465 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
70353	3.3784	1364
70349	0.4027	202

Top tissues by expression

278 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.95	gold quality
colonic epithelium	UBERON:0000397	89.46	gold quality
calcaneal tendon	UBERON:0003701	86.61	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.75	gold quality
adrenal tissue	UBERON:0018303	84.02	gold quality
right uterine tube	UBERON:0001302	83.86	gold quality
right hemisphere of cerebellum	UBERON:0014890	83.60	gold quality
cerebellar hemisphere	UBERON:0002245	83.48	gold quality
cerebellar cortex	UBERON:0002129	83.34	gold quality
prefrontal cortex	UBERON:0000451	82.97	gold quality
caudate nucleus	UBERON:0001873	81.36	gold quality
nucleus accumbens	UBERON:0001882	81.23	gold quality
left ovary	UBERON:0002119	81.10	gold quality
anterior cingulate cortex	UBERON:0009835	80.83	gold quality
right ovary	UBERON:0002118	80.80	gold quality
cingulate cortex	UBERON:0003027	80.77	gold quality
Brodmann (1909) area 23	UBERON:0013554	80.75	gold quality
lower esophagus muscularis layer	UBERON:0035833	80.74	gold quality
cerebellum	UBERON:0002037	80.73	gold quality
lower esophagus	UBERON:0013473	80.72	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.62	gold quality
middle temporal gyrus	UBERON:0002771	80.56	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	80.46	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	80.34	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	80.31	gold quality
primary visual cortex	UBERON:0002436	80.27	gold quality
right frontal lobe	UBERON:0002810	80.08	gold quality
neocortex	UBERON:0001950	79.78	gold quality
left lobe of thyroid gland	UBERON:0001120	79.76	gold quality
frontal cortex	UBERON:0001870	79.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.17

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.