EPS15-AS1

Summary

EPS15-AS1 (EPS15 antisense RNA 1, HGNC:40219) is a long non-coding RNA gene on chromosome 1p32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40219
Approved symbol	EPS15-AS1
Name	EPS15 antisense RNA 1
Location	1p32.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000227070
Ensembl biotype	lncRNA
Entrez	105378720
RNAcentral	URS00026A1C1C — lncRNA, 771 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 39 — 39 lncRNA

ENST00000415031, ENST00000426017, ENST00000702775, ENST00000828277, ENST00000828278, ENST00000828279, ENST00000828280, ENST00000828281, ENST00000828282, ENST00000828283, ENST00000828284, ENST00000828285, ENST00000828286, ENST00000828287, ENST00000828288, ENST00000828289, ENST00000828290, ENST00000828291, ENST00000828292, ENST00000828293, ENST00000828294, ENST00000828295, ENST00000828296, ENST00000828297, ENST00000828298, ENST00000828299, ENST00000828300, ENST00000828301, ENST00000828302, ENST00000828303, ENST00000828304, ENST00000828305, ENST00000828306, ENST00000828307, ENST00000828308, ENST00000828309, ENST00000828310, ENST00000828311, ENST00000828312

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415031 — 3 exons

Exon	Start	End
ENSE00003984545	51518289	51518483
ENSE00003984546	51560882	51561023
ENSE00003984547	51561471	51561651

Expression profiles

Bgee: expression breadth ubiquitous, 125 present calls, max score 95.91.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6580 / max 81.7610, expressed in 495 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
2847	1.6580	495

Top tissues by expression

125 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	95.91	gold quality
mucosa of transverse colon	UBERON:0004991	80.32	gold quality
right lobe of liver	UBERON:0001114	80.12	gold quality
liver	UBERON:0002107	79.56	gold quality
bone marrow cell	CL:0002092	79.37	gold quality
lymph node	UBERON:0000029	78.87	gold quality
duodenum	UBERON:0002114	77.65	gold quality
muscle of leg	UBERON:0001383	77.59	gold quality
gastrocnemius	UBERON:0001388	77.52	gold quality
tonsil	UBERON:0002372	76.87	gold quality
skeletal muscle tissue	UBERON:0001134	76.68	gold quality
ventricular zone	UBERON:0003053	76.55	gold quality
bone marrow	UBERON:0002371	76.52	gold quality
small intestine	UBERON:0002108	76.30	gold quality
colonic epithelium	UBERON:0000397	75.86	gold quality
small intestine Peyer’s patch	UBERON:0003454	75.79	gold quality
hindlimb stylopod muscle	UBERON:0004252	75.30	gold quality
transverse colon	UBERON:0001157	74.49	gold quality
sural nerve	UBERON:0015488	73.82	gold quality
rectum	UBERON:0001052	73.60	gold quality
prostate gland	UBERON:0002367	73.26	gold quality
right adrenal gland cortex	UBERON:0035827	72.90	gold quality
blood	UBERON:0000178	72.23	gold quality
intestine	UBERON:0000160	71.73	gold quality
vermiform appendix	UBERON:0001154	71.64	gold quality
lower esophagus mucosa	UBERON:0035834	71.61	gold quality
left adrenal gland cortex	UBERON:0035825	70.87	gold quality
colon	UBERON:0001155	70.04	gold quality
right adrenal gland	UBERON:0001233	69.71	gold quality
gall bladder	UBERON:0002110	69.50	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.