ERC2-IT1

Summary

ERC2-IT1 (ERC2 intronic transcript 1, HGNC:1229) is a long non-coding RNA gene on chromosome 3p14.3.

This gene is a putative tumor suppressor gene.

Source: NCBI Gene 711 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:1229
Approved symbol	ERC2-IT1
Name	ERC2 intronic transcript 1
Location	3p14.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	Po42
Ensembl gene	ENSG00000281708
Ensembl biotype	lncRNA
Entrez	711
RNAcentral	URS000075AB4D — lncRNA, 2264 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000629461

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000629461 — 1 exons

Exon	Start	End
ENSE00003764886	55657206	55659382

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 96.03.

Top tissues by expression

186 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	96.03	gold quality
Brodmann (1909) area 23	UBERON:0013554	72.56	gold quality
diaphragm	UBERON:0001103	70.84	gold quality
olfactory bulb	UBERON:0002264	67.47	gold quality
smooth muscle tissue	UBERON:0001135	67.33	gold quality
type B pancreatic cell	CL:0000169	67.17	gold quality
middle temporal gyrus	UBERON:0002771	66.07	silver quality
primary visual cortex	UBERON:0002436	65.18	gold quality
orbitofrontal cortex	UBERON:0004167	65.09	silver quality
bone marrow cell	CL:0002092	64.94	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	64.29	gold quality
postcentral gyrus	UBERON:0002581	64.17	gold quality
entorhinal cortex	UBERON:0002728	63.78	gold quality
epithelial cell of pancreas	CL:0000083	63.70	gold quality
superior frontal gyrus	UBERON:0002661	63.15	silver quality
cervix squamous epithelium	UBERON:0006922	63.03	gold quality
occipital lobe	UBERON:0002021	62.75	gold quality
myocardium	UBERON:0002349	62.66	gold quality
parietal lobe	UBERON:0001872	62.46	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	62.35	gold quality
Brodmann (1909) area 9	UBERON:0013540	61.85	silver quality
cerebellar vermis	UBERON:0004720	61.75	gold quality
mononuclear cell	CL:0000842	61.29	gold quality
cardiac muscle of right atrium	UBERON:0003379	60.98	gold quality
vastus lateralis	UBERON:0001379	60.96	gold quality
uterine cervix	UBERON:0000002	60.66	gold quality
left ventricle myocardium	UBERON:0006566	60.56	gold quality
cervix epithelium	UBERON:0004801	60.54	gold quality
quadriceps femoris	UBERON:0001377	60.52	gold quality
Ammon’s horn	UBERON:0001954	60.40	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.