ERCC8-AS1

Summary

ERCC8-AS1 (ERCC8 antisense RNA 1, HGNC:40220) is a long non-coding RNA gene on chromosome 5q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40220
Approved symbol	ERCC8-AS1
Name	ERCC8 antisense RNA 1
Location	5q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233847
Ensembl biotype	lncRNA
Entrez	105378991
RNAcentral	URS00026A1E8E — lncRNA, 709 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000457499, ENST00000731908

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457499 — 3 exons

Exon	Start	End
ENSE00001643709	60918295	60918427
ENSE00001683582	60919377	60919573
ENSE00004061773	60917424	60917567

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 79.14.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.14	silver quality
ganglionic eminence	UBERON:0004023	70.34	gold quality
adrenal tissue	UBERON:0018303	67.29	gold quality
left testis	UBERON:0004533	67.10	gold quality
testis	UBERON:0000473	66.47	gold quality
monocyte	CL:0000576	65.62	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	65.11	gold quality
right testis	UBERON:0004534	64.28	gold quality
calcaneal tendon	UBERON:0003701	63.22	gold quality
bone marrow	UBERON:0002371	62.74	gold quality
corpus callosum	UBERON:0002336	60.81	gold quality
stromal cell of endometrium	CL:0002255	60.13	gold quality
ectocervix	UBERON:0012249	59.69	gold quality
prefrontal cortex	UBERON:0000451	58.53	gold quality
gall bladder	UBERON:0002110	58.17	gold quality
lymph node	UBERON:0000029	57.66	gold quality
placenta	UBERON:0001987	57.29	gold quality
right ovary	UBERON:0002118	56.37	gold quality
endocervix	UBERON:0000458	56.34	gold quality
islet of Langerhans	UBERON:0000006	56.14	gold quality
blood	UBERON:0000178	56.01	gold quality
vermiform appendix	UBERON:0001154	55.69	gold quality
ovary	UBERON:0000992	55.28	gold quality
endometrium	UBERON:0001295	55.18	gold quality
fundus of stomach	UBERON:0001160	54.95	gold quality
popliteal artery	UBERON:0002250	54.85	gold quality
left ovary	UBERON:0002119	54.84	gold quality
tibial artery	UBERON:0007610	54.84	gold quality
left coronary artery	UBERON:0001626	54.67	gold quality
myometrium	UBERON:0001296	54.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.