ERICD

Summary

ERICD (E2F1-regulated inhibitor of cell death, HGNC:49404) is a long non-coding RNA gene on chromosome 8q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49404
Approved symbol	ERICD
Name	E2F1-regulated inhibitor of cell death
Location	8q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00014875, ERIC
Ensembl gene	ENSG00000280303
Ensembl biotype	lncRNA
OMIM	621290
Entrez	104355217
RNAcentral	URS00021231D0 — lncRNA, 4049 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000623655

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000623655 — 1 exons

Exon	Start	End
ENSE00003758938	140636281	140638283

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 66.92.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
adenohypophysis	UBERON:0002196	66.92	gold quality
caudate nucleus	UBERON:0001873	65.17	gold quality
stromal cell of endometrium	CL:0002255	64.70	gold quality
putamen	UBERON:0001874	64.57	gold quality
nucleus accumbens	UBERON:0001882	64.22	gold quality
pituitary gland	UBERON:0000007	64.15	gold quality
bone marrow cell	CL:0002092	64.09	silver quality
ventricular zone	UBERON:0003053	64.04	gold quality
cortical plate	UBERON:0005343	63.51	gold quality
apex of heart	UBERON:0002098	62.06	gold quality
left ovary	UBERON:0002119	61.74	gold quality
ovary	UBERON:0000992	61.48	gold quality
ganglionic eminence	UBERON:0004023	61.41	gold quality
prefrontal cortex	UBERON:0000451	61.33	gold quality
skeletal muscle tissue	UBERON:0001134	61.25	gold quality
sural nerve	UBERON:0015488	61.25	silver quality
hindlimb stylopod muscle	UBERON:0004252	60.40	gold quality
frontal cortex	UBERON:0001870	60.27	gold quality
right ovary	UBERON:0002118	59.96	gold quality
superior frontal gyrus	UBERON:0002661	59.84	gold quality
islet of Langerhans	UBERON:0000006	59.66	gold quality
right atrium auricular region	UBERON:0006631	59.50	gold quality
right frontal lobe	UBERON:0002810	59.26	gold quality
gastrocnemius	UBERON:0001388	59.13	gold quality
brain	UBERON:0000955	59.02	gold quality
cerebral cortex	UBERON:0000956	59.01	gold quality
placenta	UBERON:0001987	59.01	gold quality
muscle of leg	UBERON:0001383	58.89	gold quality
hypothalamus	UBERON:0001898	58.75	gold quality
bone marrow	UBERON:0002371	58.75	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.79

Regulation

Is transcription factor: no

Upstream regulators (CollecTRI, top): E2F1, E2F3

Literature-anchored findings (GeneRIF, showing 2)

• ERIC as a novel lncRNA that is transcriptionally regulated by E2F1 transcription factor. [XLOC_006942] (PMID:24168400)
• Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells. (PMID:32749762)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.