ESAM-AS1

Summary

ESAM-AS1 (ESAM antisense RNA 1, HGNC:55558) is a long non-coding RNA gene on chromosome 11q24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55558
Approved symbol	ESAM-AS1
Name	ESAM antisense RNA 1
Location	11q24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250073
Ensembl biotype	lncRNA
Entrez	101929340
RNAcentral	URS000075DC0A — lncRNA, 1477 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000504932, ENST00000532579, ENST00000653370, ENST00000686851, ENST00000758975, ENST00000758976, ENST00000758977, ENST00000758978, ENST00000758979, ENST00000758980, ENST00000758981, ENST00000758982

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504932 — 2 exons

Exon	Start	End
ENSE00004111342	124758908	124759413
ENSE00004111353	124764729	124765937

Expression profiles

Bgee: expression breadth ubiquitous, 173 present calls, max score 85.61.

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.61	gold quality
buccal mucosa cell	CL:0002336	81.00	gold quality
mucosa of transverse colon	UBERON:0004991	77.87	gold quality
right coronary artery	UBERON:0001625	77.82	gold quality
popliteal artery	UBERON:0002250	77.78	gold quality
tibial artery	UBERON:0007610	77.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.98	silver quality
left lobe of thyroid gland	UBERON:0001120	76.13	gold quality
right lobe of thyroid gland	UBERON:0001119	75.73	gold quality
thyroid gland	UBERON:0002046	75.51	gold quality
left coronary artery	UBERON:0001626	75.32	gold quality
coronary artery	UBERON:0001621	74.13	gold quality
aorta	UBERON:0000947	73.93	gold quality
right lung	UBERON:0002167	73.86	gold quality
metanephros cortex	UBERON:0010533	72.64	gold quality
apex of heart	UBERON:0002098	72.54	gold quality
amniotic fluid	UBERON:0000173	72.08	gold quality
lower esophagus mucosa	UBERON:0035834	72.02	gold quality
lower lobe of lung	UBERON:0008949	71.76	gold quality
upper lobe of left lung	UBERON:0008952	71.66	gold quality
monocyte	CL:0000576	71.56	gold quality
upper lobe of lung	UBERON:0008948	71.54	gold quality
leukocyte	CL:0000738	70.81	gold quality
transverse colon	UBERON:0001157	69.67	gold quality
rectum	UBERON:0001052	69.42	gold quality
thoracic aorta	UBERON:0001515	69.21	gold quality
ascending aorta	UBERON:0001496	69.05	gold quality
pancreatic ductal cell	CL:0002079	68.46	silver quality
lung	UBERON:0002048	67.93	gold quality
omental fat pad	UBERON:0010414	67.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.