ETS1-AS1

Summary

ETS1-AS1 (ETS1 antisense RNA 1, HGNC:53932) is a long non-coding RNA gene on chromosome 11q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53932
Approved symbol	ETS1-AS1
Name	ETS1 antisense RNA 1
Location	11q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	pancEts-1
Ensembl gene	ENSG00000254588
Ensembl biotype	lncRNA
Entrez	101929517
RNAcentral	URS000075B558 — lncRNA, 1395 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000525706

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000525706 — 4 exons

Exon	Start	End
ENSE00002158838	128526533	128527418
ENSE00002167056	128526142	128526315
ENSE00002182253	128529011	128529085
ENSE00002184939	128530138	128530389

Expression profiles

Bgee: expression breadth broad, 47 present calls, max score 61.56.

Top tissues by expression

161 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
colonic epithelium	UBERON:0000397	61.56	silver quality
sperm	CL:0000019	60.48	silver quality
sural nerve	UBERON:0015488	59.80	silver quality
hindlimb stylopod muscle	UBERON:0004252	56.46	silver quality
calcaneal tendon	UBERON:0003701	52.02	silver quality
body of uterus	UBERON:0009853	48.37	gold quality
monocyte	CL:0000576	48.29	silver quality
muscle of leg	UBERON:0001383	48.24	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	47.80	gold quality
uterine cervix	UBERON:0000002	47.42	gold quality
gall bladder	UBERON:0002110	45.41	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.40	silver quality
vermiform appendix	UBERON:0001154	45.07	silver quality
upper lobe of left lung	UBERON:0008952	44.78	gold quality
lower esophagus muscularis layer	UBERON:0035833	44.63	silver quality
islet of Langerhans	UBERON:0000006	44.46	silver quality
tibial artery	UBERON:0007610	43.97	silver quality
tonsil	UBERON:0002372	43.78	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
omental fat pad	UBERON:0010414	42.91	silver quality
peritoneum	UBERON:0002358	42.89	silver quality
body of stomach	UBERON:0001161	42.76	gold quality
subcutaneous adipose tissue	UBERON:0002190	42.59	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
aorta	UBERON:0000947	42.55	silver quality
adipose tissue of abdominal region	UBERON:0007808	42.54	silver quality
adrenal tissue	UBERON:0018303	42.41	silver quality
lymph node	UBERON:0000029	42.38	gold quality
gastrocnemius	UBERON:0001388	42.23	silver quality
adipose tissue	UBERON:0001013	41.86	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• High LncRNA pancEts-1 promoted the growth, invasion, and metastasis of neuroblastoma. (PMID:29311158)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.