ETS2-AS1

Summary

ETS2-AS1 (ETS2 antisense RNA 1, HGNC:56712) is a long non-coding RNA gene on chromosome 21q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56712
Approved symbol	ETS2-AS1
Name	ETS2 antisense RNA 1
Location	21q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205622
Ensembl biotype	lncRNA
Entrez	400867
RNAcentral	URS000057DA8A — lncRNA, 3823 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 81 — 81 lncRNA

ENST00000380931, ENST00000415824, ENST00000440379, ENST00000613045, ENST00000615324, ENST00000623098, ENST00000626259, ENST00000653449, ENST00000654496, ENST00000657019, ENST00000657276, ENST00000658721, ENST00000659831, ENST00000660489, ENST00000660602, ENST00000661563, ENST00000663561, ENST00000664415, ENST00000665758, ENST00000669345, ENST00000670092, ENST00000671381, ENST00000671617, ENST00000686487, ENST00000686562, ENST00000689146, ENST00000700848, ENST00000701127, ENST00000701265, ENST00000701620, ENST00000776362, ENST00000776363, ENST00000776364, ENST00000776365, ENST00000776366, ENST00000776367, ENST00000776368, ENST00000776369, ENST00000776370, ENST00000776371, ENST00000776372, ENST00000776373, ENST00000776374, ENST00000776375, ENST00000776376, ENST00000776377, ENST00000776378, ENST00000776379, ENST00000776380, ENST00000776381, ENST00000776382, ENST00000776383, ENST00000776384, ENST00000776385, ENST00000776386, ENST00000776387, ENST00000776388, ENST00000776389, ENST00000776390, ENST00000776391, ENST00000776392, ENST00000776393, ENST00000776394, ENST00000776395, ENST00000776396, ENST00000776397, ENST00000776398, ENST00000776399, ENST00000776400, ENST00000776401, ENST00000776402, ENST00000776403, ENST00000776404, ENST00000776405, ENST00000776406, ENST00000776407, ENST00000776408, ENST00000776409, ENST00000776410, ENST00000776411, ENST00000776412

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000380931 — 4 exons

Exon	Start	End
ENSE00001486856	38876087	38880372
ENSE00001543055	38923638	38923693
ENSE00001543058	38937810	38938429
ENSE00002440510	38901901	38901965

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 81.84.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
liver	UBERON:0002107	81.84	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.71	gold quality
right lobe of liver	UBERON:0001114	81.27	gold quality
colonic epithelium	UBERON:0000397	77.31	gold quality
rectum	UBERON:0001052	74.75	gold quality
skin of abdomen	UBERON:0001416	73.93	gold quality
zone of skin	UBERON:0000014	71.40	gold quality
vagina	UBERON:0000996	70.80	gold quality
duodenum	UBERON:0002114	70.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.65	gold quality
skeletal muscle tissue	UBERON:0001134	70.19	gold quality
mucosa of stomach	UBERON:0001199	70.10	gold quality
uterine cervix	UBERON:0000002	69.90	gold quality
skin of leg	UBERON:0001511	69.66	gold quality
ectocervix	UBERON:0012249	69.59	gold quality
upper lobe of left lung	UBERON:0008952	68.95	gold quality
right lung	UBERON:0002167	68.88	gold quality
lung	UBERON:0002048	68.65	gold quality
small intestine	UBERON:0002108	68.20	gold quality
sural nerve	UBERON:0015488	68.05	gold quality
endometrium	UBERON:0001295	67.89	gold quality
small intestine Peyer’s patch	UBERON:0003454	67.87	gold quality
transverse colon	UBERON:0001157	67.76	gold quality
muscle tissue	UBERON:0002385	67.60	gold quality
urinary bladder	UBERON:0001255	67.27	gold quality
monocyte	CL:0000576	66.30	gold quality
spleen	UBERON:0002106	66.13	gold quality
ganglionic eminence	UBERON:0004023	66.05	gold quality
vermiform appendix	UBERON:0001154	65.82	gold quality
intestine	UBERON:0000160	65.78	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.44
E-MTAB-9543	yes	4.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.