EVA1A-AS

Summary

EVA1A-AS (EVA1A antisense RNA, HGNC:55283) is a long non-coding RNA gene on chromosome 2p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55283
Approved symbol	EVA1A-AS
Name	EVA1A antisense RNA
Location	2p12
Locus type	RNA, long non-coding
Status	Approved
Aliases	EVA1A-AS1
Ensembl gene	ENSG00000231172
Ensembl biotype	lncRNA
Entrez	101927884
RNAcentral	URS00001AE12D — lncRNA, 1185 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000451622

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000451622 — 3 exons

Exon	Start	End
ENSE00001624443	75541738	75542706
ENSE00001715266	75540739	75540870
ENSE00003700491	75524068	75524151

Expression profiles

Bgee: expression breadth broad, 70 present calls, max score 75.89.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2316 / max 140.4189, expressed in 17 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
21095	0.2316	17

Top tissues by expression

172 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.89	gold quality
bone marrow cell	CL:0002092	70.47	silver quality
ventricular zone	UBERON:0003053	61.33	gold quality
ganglionic eminence	UBERON:0004023	59.50	gold quality
adrenal tissue	UBERON:0018303	55.93	gold quality
stromal cell of endometrium	CL:0002255	55.26	silver quality
sural nerve	UBERON:0015488	52.89	silver quality
tonsil	UBERON:0002372	51.93	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	51.49	gold quality
monocyte	CL:0000576	51.43	silver quality
gall bladder	UBERON:0002110	50.50	gold quality
liver	UBERON:0002107	50.27	silver quality
calcaneal tendon	UBERON:0003701	49.56	silver quality
adult mammalian kidney	UBERON:0000082	49.48	gold quality
testis	UBERON:0000473	48.43	gold quality
islet of Langerhans	UBERON:0000006	48.18	gold quality
kidney	UBERON:0002113	47.74	gold quality
prefrontal cortex	UBERON:0000451	47.46	silver quality
vermiform appendix	UBERON:0001154	46.75	silver quality
lower esophagus mucosa	UBERON:0035834	46.72	silver quality
pancreas	UBERON:0001264	46.65	gold quality
nasal cavity mucosa	UBERON:0001826	45.38	gold quality
muscle of leg	UBERON:0001383	45.33	silver quality
body of pancreas	UBERON:0001150	44.66	silver quality
gastrocnemius	UBERON:0001388	44.55	silver quality
smooth muscle tissue	UBERON:0001135	44.26	gold quality
bone marrow	UBERON:0002371	44.04	silver quality
right lobe of liver	UBERON:0001114	43.77	silver quality
heart left ventricle	UBERON:0002084	43.59	silver quality
left lobe of thyroid gland	UBERON:0001120	43.38	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.29

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Myc/Max dependent intronic long antisense noncoding RNA, EVA1A-AS, suppresses the expression of Myc/Max dependent anti-proliferating gene EVA1A in a U2 dependent manner. (PMID:31754186)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.