EVX1-AS

Summary

EVX1-AS (EVX1 antisense RNA, HGNC:40223) is a long non-coding RNA gene on chromosome 7p15.2.

Predicted to enable chromatin binding activity. Predicted to be part of histone methyltransferase complex.

Source: NCBI Gene 101410536 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40223
Approved symbol	EVX1-AS
Name	EVX1 antisense RNA
Location	7p15.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	EVX1-AS1, EVX1AS
Ensembl gene	ENSG00000253405
Ensembl biotype	lncRNA
Entrez	101410536
RNAcentral	URS00006213E8 — lncRNA, 480 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000517726, ENST00000519050, ENST00000519218, ENST00000830135

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517726 — 4 exons

Exon	Start	End
ENSE00002100226	27241915	27242010
ENSE00002101220	27241549	27241641
ENSE00002111126	27241429	27241450
ENSE00002114195	27246961	27247229

Expression profiles

Bgee: expression breadth broad, 90 present calls, max score 96.00.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0696 / max 41.9223, expressed in 27 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
83337	0.0385	7
83338	0.0311	11

Top tissues by expression

90 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	96.00	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.31	gold quality
vagina	UBERON:0000996	78.48	gold quality
prostate gland	UBERON:0002367	78.37	gold quality
right testis	UBERON:0004534	74.46	gold quality
left testis	UBERON:0004533	74.25	gold quality
urinary bladder	UBERON:0001255	73.76	gold quality
testis	UBERON:0000473	73.71	gold quality
endocervix	UBERON:0000458	70.24	gold quality
ectocervix	UBERON:0012249	69.38	gold quality
muscle tissue	UBERON:0002385	67.67	gold quality
sural nerve	UBERON:0015488	67.23	gold quality
right adrenal gland	UBERON:0001233	62.20	gold quality
smooth muscle tissue	UBERON:0001135	61.58	gold quality
adrenal gland	UBERON:0002369	61.02	gold quality
left adrenal gland cortex	UBERON:0035825	61.02	gold quality
right adrenal gland cortex	UBERON:0035827	60.87	gold quality
left adrenal gland	UBERON:0001234	59.79	gold quality
liver	UBERON:0002107	57.93	gold quality
prefrontal cortex	UBERON:0000451	57.69	gold quality
rectum	UBERON:0001052	56.67	gold quality
multicellular organism	UBERON:0000468	56.58	gold quality
monocyte	CL:0000576	52.98	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.55	gold quality
endometrium	UBERON:0001295	51.77	gold quality
metanephros cortex	UBERON:0010533	50.20	gold quality
myometrium	UBERON:0001296	50.02	gold quality
left uterine tube	UBERON:0001303	49.94	gold quality
transverse colon	UBERON:0001157	49.72	gold quality
body of uterus	UBERON:0009853	49.72	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.01

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.