FAM106A

Summary

FAM106A (family with sequence similarity 106 member A, HGNC:25682) is a long non-coding RNA gene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:25682
Approved symbol	FAM106A
Name	family with sequence similarity 106 member A
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ11800
Ensembl gene	ENSG00000273018
Ensembl biotype	lncRNA
Entrez	80039
RNAcentral	URS000075F0DD — lncRNA, 2281 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 96 — 89 lncRNA, 7 retained_intron

ENST00000392176, ENST00000412260, ENST00000414432, ENST00000420856, ENST00000421108, ENST00000425211, ENST00000445752, ENST00000446853, ENST00000450277, ENST00000455629, ENST00000577869, ENST00000578409, ENST00000581595, ENST00000608141, ENST00000608216, ENST00000608313, ENST00000608376, ENST00000608385, ENST00000608726, ENST00000609193, ENST00000609272, ENST00000609578, ENST00000609768, ENST00000609805, ENST00000609831, ENST00000609832, ENST00000609959, ENST00000610104, ENST00000610155, ENST00000613211, ENST00000618081, ENST00000621104, ENST00000684795, ENST00000687755, ENST00000689092, ENST00000689807, ENST00000700961, ENST00000701781, ENST00000701957, ENST00000702028, ENST00000702230, ENST00000762613, ENST00000762808, ENST00000782081, ENST00000782082, ENST00000782083, ENST00000782084, ENST00000782085, ENST00000782086, ENST00000782087, ENST00000782088, ENST00000782089, ENST00000782090, ENST00000808106, ENST00000808107, ENST00000808108, ENST00000808109, ENST00000808110, ENST00000808111, ENST00000808112, ENST00000808113, ENST00000808114, ENST00000808115, ENST00000808116, ENST00000808117, ENST00000808118, ENST00000808119, ENST00000808120, ENST00000808121, ENST00000808122, ENST00000808123, ENST00000808124, ENST00000808125, ENST00000808126, ENST00000808127, ENST00000808128, ENST00000808129, ENST00000808130, ENST00000808131, ENST00000808132, ENST00000808133, ENST00000808134, ENST00000808135, ENST00000808136, ENST00000808137, ENST00000808138, ENST00000808139, ENST00000808140, ENST00000808141, ENST00000808142, ENST00000808143, ENST00000808144, ENST00000808145, ENST00000808146, ENST00000808147, ENST00000808148

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000392176 — 1 exons

Exon	Start	End
ENSE00002212610	18524566	18526846

Expression profiles

Bgee: expression breadth ubiquitous, 172 present calls, max score 95.63.

Top tissues by expression

270 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	95.63	gold quality
buccal mucosa cell	CL:0002336	95.41	gold quality
cerebellar hemisphere	UBERON:0002245	94.38	gold quality
cerebellar cortex	UBERON:0002129	94.29	gold quality
mucosa of stomach	UBERON:0001199	92.81	gold quality
right testis	UBERON:0004534	91.03	gold quality
cerebellum	UBERON:0002037	91.02	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.57	gold quality
left testis	UBERON:0004533	90.38	gold quality
body of pancreas	UBERON:0001150	90.08	gold quality
colonic epithelium	UBERON:0000397	89.72	gold quality
left ovary	UBERON:0002119	88.76	gold quality
body of uterus	UBERON:0009853	87.41	gold quality
testis	UBERON:0000473	87.27	gold quality
right uterine tube	UBERON:0001302	87.23	gold quality
left uterine tube	UBERON:0001303	87.16	gold quality
tibial nerve	UBERON:0001323	87.01	gold quality
right ovary	UBERON:0002118	86.95	gold quality
right frontal lobe	UBERON:0002810	86.70	gold quality
right coronary artery	UBERON:0001625	86.35	gold quality
lower esophagus muscularis layer	UBERON:0035833	86.20	gold quality
lower esophagus	UBERON:0013473	86.16	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	86.02	gold quality
adenohypophysis	UBERON:0002196	85.95	gold quality
muscle layer of sigmoid colon	UBERON:0035805	85.88	gold quality
descending thoracic aorta	UBERON:0002345	85.86	gold quality
thoracic aorta	UBERON:0001515	85.54	gold quality
ascending aorta	UBERON:0001496	85.47	gold quality
aorta	UBERON:0000947	84.83	gold quality
endocervix	UBERON:0000458	84.63	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.95

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.