FAM106B

Summary

FAM106B (family with sequence similarity 106 member B, HGNC:32450) is a processed pseudogene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (processed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32450
Approved symbol	FAM106B
Name	family with sequence similarity 106 member B
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000287751
Ensembl biotype	processed_pseudogene
Entrez	100996259
RNAcentral	URS00021EDA07 — lncRNA, 1483 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 processed_pseudogene

ENST00000667406

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000667406 — 1 exons

Exon	Start	End
ENSE00003855401	20417450	20417956

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 93.26.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.26	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.56	gold quality
right hemisphere of cerebellum	UBERON:0014890	66.68	gold quality
cerebellum	UBERON:0002037	63.03	gold quality
cerebellar cortex	UBERON:0002129	62.98	gold quality
cerebellar hemisphere	UBERON:0002245	62.75	gold quality
sural nerve	UBERON:0015488	57.23	gold quality
right frontal lobe	UBERON:0002810	53.52	gold quality
left testis	UBERON:0004533	53.30	gold quality
bone marrow cell	CL:0002092	52.57	gold quality
testis	UBERON:0000473	52.46	gold quality
cortical plate	UBERON:0005343	51.96	gold quality
ventricular zone	UBERON:0003053	50.60	gold quality
superior frontal gyrus	UBERON:0002661	50.51	gold quality
right testis	UBERON:0004534	49.83	gold quality
right lung	UBERON:0002167	47.07	gold quality
skeletal muscle tissue	UBERON:0001134	46.94	gold quality
mucosa of transverse colon	UBERON:0004991	46.72	gold quality
Brodmann (1909) area 9	UBERON:0013540	46.42	gold quality
ganglionic eminence	UBERON:0004023	46.35	gold quality
thoracic aorta	UBERON:0001515	45.62	gold quality
ascending aorta	UBERON:0001496	45.47	gold quality
frontal cortex	UBERON:0001870	45.27	gold quality
colonic epithelium	UBERON:0000397	44.76	gold quality
bone marrow	UBERON:0002371	44.33	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	43.17	gold quality
brain	UBERON:0000955	42.95	gold quality
cerebral cortex	UBERON:0000956	42.86	gold quality
endometrium	UBERON:0001295	42.53	gold quality
corpus callosum	UBERON:0002336	42.40	silver quality

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.