FAM135A-AS1

Summary

FAM135A-AS1 (FAM135A antisense RNA 1, HGNC:40955) is a long non-coding RNA gene on chromosome 6q13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40955
Approved symbol	FAM135A-AS1
Name	FAM135A antisense RNA 1
Location	6q13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224349
Ensembl biotype	lncRNA
Entrez	105377849
RNAcentral	URS0000BC43C8 — lncRNA, 369 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000448363, ENST00000747741, ENST00000747742, ENST00000747743

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000448363 — 2 exons

Exon	Start	End
ENSE00004089892	70413837	70413959
ENSE00004089896	70412823	70413062

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 76.29.

Top tissues by expression

109 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	76.29	gold quality
testis	UBERON:0000473	74.81	gold quality
right testis	UBERON:0004534	73.63	gold quality
ganglionic eminence	UBERON:0004023	68.58	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.48	gold quality
lymph node	UBERON:0000029	61.52	gold quality
prefrontal cortex	UBERON:0000451	60.45	gold quality
islet of Langerhans	UBERON:0000006	59.98	gold quality
monocyte	CL:0000576	59.47	gold quality
tonsil	UBERON:0002372	58.65	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	58.16	gold quality
muscle tissue	UBERON:0002385	58.12	gold quality
urinary bladder	UBERON:0001255	57.91	gold quality
calcaneal tendon	UBERON:0003701	57.73	gold quality
lower esophagus mucosa	UBERON:0035834	57.40	gold quality
primary visual cortex	UBERON:0002436	57.12	gold quality
prostate gland	UBERON:0002367	56.86	gold quality
kidney	UBERON:0002113	56.48	gold quality
muscle of leg	UBERON:0001383	55.65	gold quality
right uterine tube	UBERON:0001302	55.28	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	55.04	gold quality
cortex of kidney	UBERON:0001225	54.98	gold quality
substantia nigra	UBERON:0002038	54.94	gold quality
superior frontal gyrus	UBERON:0002661	54.91	gold quality
liver	UBERON:0002107	54.80	gold quality
adult mammalian kidney	UBERON:0000082	54.35	gold quality
blood	UBERON:0000178	54.15	gold quality
smooth muscle tissue	UBERON:0001135	53.99	gold quality
gastrocnemius	UBERON:0001388	53.95	gold quality
corpus callosum	UBERON:0002336	53.64	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.50

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.