FAM138A

Summary

FAM138A (family with sequence similarity 138 member A, HGNC:32334) is a long non-coding RNA gene on chromosome 1p36.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32334
Approved symbol	FAM138A
Name	family with sequence similarity 138 member A
Location	1p36.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	F379
Ensembl gene	ENSG00000237613
Ensembl biotype	lncRNA
Entrez	645520
RNAcentral	URS0000311D9A — lncRNA, 1130 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000417324, ENST00000461467, ENST00000834250, ENST00000834251, ENST00000834252, ENST00000834253, ENST00000834254

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000417324 — 3 exons

Exon	Start	End
ENSE00001669267	35277	35481
ENSE00004251632	35721	36267
ENSE00004251639	34554	35174

Expression profiles

Bgee: expression breadth broad, 94 present calls, max score 79.57.

Top tissues by expression

94 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	79.57	gold quality
skeletal muscle tissue	UBERON:0001134	64.61	gold quality
vermiform appendix	UBERON:0001154	57.48	gold quality
monocyte	CL:0000576	57.31	gold quality
liver	UBERON:0002107	55.57	silver quality
bone marrow	UBERON:0002371	55.14	gold quality
blood	UBERON:0000178	54.60	gold quality
right lobe of liver	UBERON:0001114	54.50	gold quality
primary visual cortex	UBERON:0002436	54.47	gold quality
fundus of stomach	UBERON:0001160	53.35	gold quality
lymph node	UBERON:0000029	53.15	gold quality
calcaneal tendon	UBERON:0003701	52.14	silver quality
left coronary artery	UBERON:0001626	51.79	gold quality
pancreas	UBERON:0001264	51.43	gold quality
islet of Langerhans	UBERON:0000006	51.15	gold quality
duodenum	UBERON:0002114	51.15	gold quality
body of pancreas	UBERON:0001150	51.10	gold quality
muscle of leg	UBERON:0001383	51.10	gold quality
urinary bladder	UBERON:0001255	50.65	gold quality
gastrocnemius	UBERON:0001388	50.37	gold quality
superior frontal gyrus	UBERON:0002661	50.17	gold quality
prefrontal cortex	UBERON:0000451	48.82	gold quality
heart left ventricle	UBERON:0002084	48.78	gold quality
endometrium	UBERON:0001295	48.16	gold quality
adrenal tissue	UBERON:0018303	47.83	gold quality
heart	UBERON:0000948	47.74	gold quality
gall bladder	UBERON:0002110	47.63	gold quality
kidney	UBERON:0002113	47.55	silver quality
descending thoracic aorta	UBERON:0002345	46.83	gold quality
hypothalamus	UBERON:0001898	46.78	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): FAM138F (ENSG00000282591)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.