FAM138C

Summary

FAM138C (family with sequence similarity 138 member C, HGNC:32333) is a long non-coding RNA gene on chromosome 9p24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32333
Approved symbol	FAM138C
Name	family with sequence similarity 138 member C
Location	9p24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	F379
Ensembl gene	ENSG00000218839
Ensembl biotype	lncRNA
Entrez	654835
RNAcentral	URS0000759EE0 — lncRNA, 1130 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000305248, ENST00000449442, ENST00000646920

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000305248 — 2 exons

Exon	Start	End
ENSE00001729583	34965	35264
ENSE00001861639	35504	35871

Expression profiles

Bgee: expression breadth ubiquitous, 111 present calls, max score 83.99.

Top tissues by expression

111 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.99	gold quality
tonsil	UBERON:0002372	60.83	silver quality
cortical plate	UBERON:0005343	59.04	gold quality
lymph node	UBERON:0000029	58.44	gold quality
bone marrow	UBERON:0002371	58.02	gold quality
monocyte	CL:0000576	57.09	gold quality
blood	UBERON:0000178	56.97	gold quality
skeletal muscle tissue	UBERON:0001134	55.66	gold quality
myometrium	UBERON:0001296	54.64	gold quality
primary visual cortex	UBERON:0002436	54.13	gold quality
placenta	UBERON:0001987	53.96	gold quality
prefrontal cortex	UBERON:0000451	53.38	gold quality
cortex of kidney	UBERON:0001225	52.71	gold quality
liver	UBERON:0002107	52.31	silver quality
urinary bladder	UBERON:0001255	52.30	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.29	gold quality
islet of Langerhans	UBERON:0000006	52.25	gold quality
hindlimb stylopod muscle	UBERON:0004252	52.22	gold quality
adult mammalian kidney	UBERON:0000082	52.19	gold quality
kidney	UBERON:0002113	51.91	gold quality
fundus of stomach	UBERON:0001160	51.41	gold quality
body of uterus	UBERON:0009853	50.94	gold quality
right ovary	UBERON:0002118	50.78	gold quality
gall bladder	UBERON:0002110	50.44	gold quality
ectocervix	UBERON:0012249	49.86	gold quality
muscle of leg	UBERON:0001383	49.64	gold quality
omental fat pad	UBERON:0010414	49.56	gold quality
lower esophagus mucosa	UBERON:0035834	49.54	gold quality
heart left ventricle	UBERON:0002084	49.33	gold quality
lower esophagus	UBERON:0013473	49.29	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.