FAM138D

Summary

FAM138D (family with sequence similarity 138 member D, HGNC:33583) is a long non-coding RNA gene on chromosome 12p13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:33583
Approved symbol	FAM138D
Name	family with sequence similarity 138 member D
Location	12p13.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	F379
Ensembl gene	ENSG00000249054
Ensembl biotype	lncRNA
Entrez	677784
RNAcentral	URS000075BD80 — lncRNA, 1126 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000504074, ENST00000546223

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504074 — 3 exons

Exon	Start	End
ENSE00002027834	36602	37222
ENSE00002050265	37325	37529
ENSE00002076759	37773	38133

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 75.24.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.24	silver quality
sural nerve	UBERON:0015488	75.02	gold quality
monocyte	CL:0000576	56.94	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.67	silver quality
prefrontal cortex	UBERON:0000451	52.64	silver quality
blood	UBERON:0000178	51.11	gold quality
Brodmann (1909) area 9	UBERON:0013540	47.64	gold quality
vermiform appendix	UBERON:0001154	47.60	gold quality
endocervix	UBERON:0000458	47.37	gold quality
liver	UBERON:0002107	46.76	silver quality
muscle of leg	UBERON:0001383	46.71	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	46.07	gold quality
frontal cortex	UBERON:0001870	46.04	silver quality
myometrium	UBERON:0001296	45.86	gold quality
lymph node	UBERON:0000029	45.65	silver quality
right lobe of liver	UBERON:0001114	45.59	silver quality
gastrocnemius	UBERON:0001388	45.41	silver quality
smooth muscle tissue	UBERON:0001135	45.22	silver quality
heart left ventricle	UBERON:0002084	44.76	gold quality
temporal lobe	UBERON:0001871	44.13	silver quality
lower esophagus muscularis layer	UBERON:0035833	44.04	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	44.03	gold quality
lower esophagus	UBERON:0013473	43.97	gold quality
apex of heart	UBERON:0002098	43.79	silver quality
esophagus	UBERON:0001043	43.58	gold quality
body of uterus	UBERON:0009853	43.57	silver quality
urinary bladder	UBERON:0001255	43.44	silver quality
islet of Langerhans	UBERON:0000006	43.33	silver quality
ovary	UBERON:0000992	43.26	silver quality
muscle layer of sigmoid colon	UBERON:0035805	43.25	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.