FAM138E

Summary

FAM138E (family with sequence similarity 138 member E, HGNC:32335) is a long non-coding RNA gene on chromosome 15q26.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32335
Approved symbol	FAM138E
Name	family with sequence similarity 138 member E
Location	15q26.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	F379
Ensembl gene	ENSG00000248893
Ensembl biotype	lncRNA
Entrez	100124412
RNAcentral	URS000075CB8E — lncRNA, 1130 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000507796, ENST00000559252, ENST00000743244, ENST00000743245, ENST00000743246, ENST00000743247, ENST00000743248

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000507796 — 3 exons

Exon	Start	End
ENSE00002518347	101955485	101955689
ENSE00004081419	101955792	101956412
ENSE00004081425	101954699	101955245

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 63.06.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.06	gold quality
ventricular zone	UBERON:0003053	60.36	gold quality
skeletal muscle tissue	UBERON:0001134	60.15	silver quality
prefrontal cortex	UBERON:0000451	58.37	gold quality
stromal cell of endometrium	CL:0002255	55.65	gold quality
myometrium	UBERON:0001296	55.58	gold quality
liver	UBERON:0002107	55.46	silver quality
duodenum	UBERON:0002114	54.51	gold quality
monocyte	CL:0000576	54.49	gold quality
endometrium	UBERON:0001295	53.73	gold quality
bone marrow	UBERON:0002371	53.17	silver quality
blood	UBERON:0000178	52.29	gold quality
right lobe of liver	UBERON:0001114	51.74	gold quality
lymph node	UBERON:0000029	51.64	gold quality
muscle of leg	UBERON:0001383	51.38	gold quality
islet of Langerhans	UBERON:0000006	50.33	gold quality
metanephros cortex	UBERON:0010533	50.16	gold quality
placenta	UBERON:0001987	50.12	gold quality
urinary bladder	UBERON:0001255	50.00	gold quality
smooth muscle tissue	UBERON:0001135	49.85	gold quality
adrenal tissue	UBERON:0018303	49.69	gold quality
gastrocnemius	UBERON:0001388	49.51	gold quality
amygdala	UBERON:0001876	48.98	gold quality
body of pancreas	UBERON:0001150	48.93	gold quality
stomach	UBERON:0000945	48.87	gold quality
heart left ventricle	UBERON:0002084	48.77	gold quality
gall bladder	UBERON:0002110	47.63	gold quality
fallopian tube	UBERON:0003889	47.03	gold quality
adrenal gland	UBERON:0002369	46.91	gold quality
putamen	UBERON:0001874	46.89	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.