FAM157A

Summary

FAM157A (family with sequence similarity 157 member A, HGNC:34079) is a unprocessed pseudogene on chromosome 3q29.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:34079
Approved symbol	FAM157A
Name	family with sequence similarity 157 member A
Location	3q29
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236438
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	728262
RNAcentral	URS0000ABD871 — lncRNA, 6879 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000615155

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000615155 — 5 exons

Exon	Start	End
ENSE00001784598	198180755	198180864
ENSE00002490158	198186449	198186514
ENSE00003509480	198189837	198189929
ENSE00003788292	198190289	198190365
ENSE00003788513	198188672	198188730

Expression profiles

Bgee: expression breadth ubiquitous, 133 present calls, max score 97.80.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	97.80	gold quality
lower esophagus mucosa	UBERON:0035834	93.68	gold quality
right testis	UBERON:0004534	91.73	gold quality
left testis	UBERON:0004533	91.37	gold quality
granulocyte	CL:0000094	91.09	gold quality
spleen	UBERON:0002106	89.82	gold quality
testis	UBERON:0000473	89.50	gold quality
esophagus mucosa	UBERON:0002469	87.98	gold quality
bone marrow cell	CL:0002092	84.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	84.96	gold quality
bone marrow	UBERON:0002371	84.61	gold quality
upper lobe of left lung	UBERON:0008952	82.35	gold quality
right lung	UBERON:0002167	82.14	gold quality
leukocyte	CL:0000738	82.00	gold quality
monocyte	CL:0000576	81.90	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.89	gold quality
mucosa of stomach	UBERON:0001199	80.19	gold quality
esophagus	UBERON:0001043	79.44	gold quality
lung	UBERON:0002048	79.15	gold quality
adrenal tissue	UBERON:0018303	79.08	gold quality
minor salivary gland	UBERON:0001830	78.91	gold quality
primary visual cortex	UBERON:0002436	78.52	gold quality
saliva-secreting gland	UBERON:0001044	78.20	gold quality
prostate gland	UBERON:0002367	78.09	gold quality
body of pancreas	UBERON:0001150	78.01	gold quality
vermiform appendix	UBERON:0001154	77.89	gold quality
left uterine tube	UBERON:0001303	77.54	gold quality
pituitary gland	UBERON:0000007	77.50	gold quality
adenohypophysis	UBERON:0002196	77.28	gold quality
hindlimb stylopod muscle	UBERON:0004252	76.96	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9801	yes	209.24
E-ANND-3	yes	3.06

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.