FAM157D

Summary

FAM157D (family with sequence similarity 157 member D, HGNC:56252) is a long non-coding RNA gene on chromosome 7p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56252
Approved symbol	FAM157D
Name	family with sequence similarity 157 member D
Location	7p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000282572
Ensembl biotype	lncRNA
Entrez	125775238
RNAcentral	URS0002A14711 — lncRNA, 1190 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000632586, ENST00000633163, ENST00000635373, ENST00000692479, ENST00000702206, ENST00000821996, ENST00000821997, ENST00000821998, ENST00000821999, ENST00000822000, ENST00000822001, ENST00000822002, ENST00000822003, ENST00000822004, ENST00000822005, ENST00000822006, ENST00000822007, ENST00000822008, ENST00000822009, ENST00000822010, ENST00000822011, ENST00000822012, ENST00000822013, ENST00000822128, ENST00000822129, ENST00000822130, ENST00000822131, ENST00000822132, ENST00000822133, ENST00000822134, ENST00000822135, ENST00000822136, ENST00000822137, ENST00000822138, ENST00000822139

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000632586 — 3 exons

Exon	Start	End
ENSE00003775856	31390	31606
ENSE00003776542	33681	33792
ENSE00003783867	35335	35489

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 91.82.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	91.82	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.05	gold quality
bone marrow	UBERON:0002371	85.24	gold quality
monocyte	CL:0000576	83.60	gold quality
bone marrow cell	CL:0002092	82.73	gold quality
leukocyte	CL:0000738	82.37	gold quality
granulocyte	CL:0000094	78.94	gold quality
spleen	UBERON:0002106	73.58	gold quality
vermiform appendix	UBERON:0001154	73.26	gold quality
sural nerve	UBERON:0015488	70.15	gold quality
right lung	UBERON:0002167	69.57	gold quality
colonic epithelium	UBERON:0000397	69.35	silver quality
upper lobe of left lung	UBERON:0008952	68.33	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.99	gold quality
esophagus mucosa	UBERON:0002469	66.85	gold quality
cortical plate	UBERON:0005343	66.62	gold quality
lung	UBERON:0002048	66.30	gold quality
placenta	UBERON:0001987	64.47	gold quality
ganglionic eminence	UBERON:0004023	63.13	gold quality
urinary bladder	UBERON:0001255	61.80	gold quality
esophagus	UBERON:0001043	61.68	gold quality
lower esophagus mucosa	UBERON:0035834	61.40	gold quality
omental fat pad	UBERON:0010414	60.58	gold quality
adrenal tissue	UBERON:0018303	59.82	gold quality
mucosa of stomach	UBERON:0001199	59.77	gold quality
saliva-secreting gland	UBERON:0001044	59.70	gold quality
minor salivary gland	UBERON:0001830	59.62	gold quality
lymph node	UBERON:0000029	59.57	gold quality
descending thoracic aorta	UBERON:0002345	59.28	gold quality
liver	UBERON:0002107	59.16	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.49

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.