FAM170B-AS1

Summary

FAM170B-AS1 (FAM170B antisense RNA 1, HGNC:45006) is a long non-coding RNA gene on chromosome 10q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45006
Approved symbol	FAM170B-AS1
Name	FAM170B antisense RNA 1
Location	10q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234736
Ensembl biotype	lncRNA
Entrez	100506733
RNAcentral	URS000075A8FF — lncRNA, 2013 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000435809, ENST00000440054, ENST00000442525, ENST00000443389, ENST00000815548, ENST00000815549, ENST00000815550, ENST00000815551, ENST00000815552, ENST00000815553

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435809 — 4 exons

Exon	Start	End
ENSE00001630843	49150805	49151547
ENSE00001645795	49135877	49136081
ENSE00001749236	49141253	49141367
ENSE00004217610	49121854	49122276

Expression profiles

Bgee: expression breadth broad, 71 present calls, max score 87.28.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0126 / max 13.0815, expressed in 3 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
104871	0.0126	3

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.28	silver quality
mucosa of paranasal sinus	UBERON:0005030	79.33	gold quality
germinal epithelium of ovary	UBERON:0001304	70.77	gold quality
superficial temporal artery	UBERON:0001614	68.98	gold quality
left testis	UBERON:0004533	68.44	gold quality
right testis	UBERON:0004534	67.11	gold quality
gingival epithelium	UBERON:0001949	66.47	gold quality
testis	UBERON:0000473	66.30	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	64.04	gold quality
buccal mucosa cell	CL:0002336	60.74	gold quality
secondary oocyte	CL:0000655	60.02	gold quality
gingiva	UBERON:0001828	59.35	gold quality
sperm	CL:0000019	56.95	silver quality
oocyte	CL:0000023	56.79	gold quality
vena cava	UBERON:0004087	56.53	gold quality
parotid gland	UBERON:0001831	55.48	gold quality
vastus lateralis	UBERON:0001379	54.40	gold quality
lower lobe of lung	UBERON:0008949	54.34	silver quality
tonsil	UBERON:0002372	54.31	gold quality
quadriceps femoris	UBERON:0001377	54.08	gold quality
myocardium	UBERON:0002349	53.66	gold quality
tendon of biceps brachii	UBERON:0008188	52.99	gold quality
tendon	UBERON:0000043	52.69	gold quality
nasal cavity epithelium	UBERON:0005384	52.59	gold quality
esophagus squamous epithelium	UBERON:0006920	51.81	gold quality
deltoid	UBERON:0001476	50.82	gold quality
monocyte	CL:0000576	50.00	silver quality
cardia of stomach	UBERON:0001162	49.99	gold quality
subthalamic nucleus	UBERON:0001906	49.37	gold quality
muscle of leg	UBERON:0001383	49.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.77

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.