FAM182B

Summary

FAM182B (family with sequence similarity 182 member B, HGNC:34503) is a long non-coding RNA gene on chromosome 20p11.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:34503
Approved symbol	FAM182B
Name	family with sequence similarity 182 member B
Location	20p11.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000175170
Ensembl biotype	lncRNA
Entrez	728882
RNAcentral	URS000075BB79 — lncRNA, 5481 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 132 — 132 lncRNA

ENST00000376403, ENST00000376404, ENST00000424021, ENST00000453481, ENST00000478164, ENST00000485279, ENST00000582267, ENST00000584071, ENST00000584356, ENST00000657325, ENST00000657987, ENST00000658073, ENST00000659462, ENST00000661999, ENST00000662668, ENST00000662978, ENST00000663181, ENST00000663313, ENST00000665932, ENST00000666588, ENST00000670090, ENST00000670112, ENST00000771697, ENST00000771698, ENST00000771699, ENST00000771700, ENST00000771701, ENST00000771702, ENST00000771703, ENST00000771704, ENST00000771705, ENST00000771706, ENST00000771707, ENST00000771708, ENST00000771709, ENST00000771710, ENST00000771711, ENST00000771712, ENST00000771713, ENST00000771714, ENST00000771715, ENST00000771716, ENST00000771717, ENST00000771718, ENST00000771719, ENST00000771720, ENST00000771721, ENST00000771722, ENST00000771723, ENST00000771724, ENST00000771725, ENST00000771726, ENST00000771727, ENST00000771728, ENST00000771729, ENST00000771730, ENST00000771731, ENST00000771732, ENST00000771733, ENST00000771734, ENST00000771735, ENST00000771736, ENST00000771737, ENST00000771738, ENST00000771739, ENST00000771740, ENST00000771741, ENST00000771742, ENST00000771743, ENST00000771744, ENST00000771745, ENST00000771746, ENST00000771747, ENST00000771748, ENST00000771749, ENST00000771750, ENST00000771751, ENST00000771752, ENST00000771753, ENST00000771754, ENST00000771755, ENST00000771756, ENST00000771757, ENST00000771758, ENST00000771759, ENST00000771760, ENST00000771761, ENST00000771762, ENST00000771763, ENST00000771764, ENST00000771765, ENST00000771766, ENST00000771767, ENST00000771768, ENST00000771769, ENST00000771770, ENST00000771771, ENST00000771772, ENST00000771773, ENST00000771774, ENST00000771775, ENST00000771776, ENST00000771777, ENST00000771778, ENST00000771779, ENST00000771780, ENST00000771781, ENST00000771782, ENST00000771783, ENST00000771784, ENST00000771785, ENST00000771786, ENST00000771787, ENST00000771788, ENST00000771789, ENST00000771790, ENST00000771791, ENST00000771792, ENST00000771793, ENST00000771794, ENST00000771795, ENST00000771796, ENST00000771797, ENST00000771798, ENST00000771799, ENST00000771800, ENST00000771801, ENST00000771802, ENST00000771803, ENST00000771804, ENST00000771805, ENST00000771806

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000376403 — 3 exons

Exon	Start	End
ENSE00003459524	25848705	25848948
ENSE00004135074	25774016	25775312
ENSE00004135131	25863060	25863256

Expression profiles

Bgee: expression breadth ubiquitous, 181 present calls, max score 95.17.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3177 / max 13.6647, expressed in 178 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
186812	0.3177	178

Top tissues by expression

283 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	95.17	gold quality
sperm	CL:0000019	91.50	gold quality
left testis	UBERON:0004533	91.34	gold quality
right testis	UBERON:0004534	90.49	gold quality
ventricular zone	UBERON:0003053	90.30	gold quality
male germ cell	CL:0000015	89.26	gold quality
testis	UBERON:0000473	88.31	gold quality
right hemisphere of cerebellum	UBERON:0014890	85.93	gold quality
cerebellar hemisphere	UBERON:0002245	85.55	gold quality
cerebellar cortex	UBERON:0002129	85.37	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.11	gold quality
cerebellum	UBERON:0002037	83.06	gold quality
pancreatic ductal cell	CL:0002079	82.31	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.81	gold quality
ganglionic eminence	UBERON:0004023	80.19	gold quality
right uterine tube	UBERON:0001302	80.09	gold quality
right frontal lobe	UBERON:0002810	79.98	gold quality
nucleus accumbens	UBERON:0001882	79.02	gold quality
caudate nucleus	UBERON:0001873	78.70	gold quality
prefrontal cortex	UBERON:0000451	78.46	gold quality
adenohypophysis	UBERON:0002196	78.15	gold quality
pituitary gland	UBERON:0000007	77.46	gold quality
amygdala	UBERON:0001876	77.40	gold quality
cingulate cortex	UBERON:0003027	77.23	gold quality
anterior cingulate cortex	UBERON:0009835	77.06	gold quality
putamen	UBERON:0001874	76.66	gold quality
Brodmann (1909) area 9	UBERON:0013540	76.50	gold quality
neocortex	UBERON:0001950	76.16	gold quality
frontal cortex	UBERON:0001870	75.92	gold quality
hypothalamus	UBERON:0001898	75.90	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.96

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.