FAM215B

Summary

FAM215B (family with sequence similarity 215 member B, HGNC:43639) is a long non-coding RNA gene on chromosome 17q21.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43639
Approved symbol	FAM215B
Name	family with sequence similarity 215 member B
Location	17q21.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	ARL17A-IT1
Ensembl gene	ENSG00000232300
Ensembl biotype	lncRNA
Entrez	644297
RNAcentral	URS0000234DB3 — lncRNA, 2183 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000458392

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000458392 — 2 exons

Exon	Start	End
ENSE00001672154	46562469	46562795
ENSE00001703948	46558830	46560685

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 81.07.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	81.07	gold quality
right uterine tube	UBERON:0001302	78.83	gold quality
cerebellum	UBERON:0002037	78.59	gold quality
cerebellar cortex	UBERON:0002129	78.54	gold quality
cerebellar hemisphere	UBERON:0002245	78.43	gold quality
right hemisphere of cerebellum	UBERON:0014890	78.07	gold quality
bone marrow	UBERON:0002371	77.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.27	gold quality
lower esophagus mucosa	UBERON:0035834	76.15	gold quality
colonic epithelium	UBERON:0000397	75.84	gold quality
monocyte	CL:0000576	74.86	gold quality
skeletal muscle tissue	UBERON:0001134	74.70	gold quality
leukocyte	CL:0000738	74.48	gold quality
sural nerve	UBERON:0015488	74.43	gold quality
pituitary gland	UBERON:0000007	73.96	gold quality
ganglionic eminence	UBERON:0004023	73.88	gold quality
tonsil	UBERON:0002372	73.46	gold quality
adenohypophysis	UBERON:0002196	73.04	gold quality
blood	UBERON:0000178	72.77	gold quality
muscle tissue	UBERON:0002385	72.65	gold quality
ventricular zone	UBERON:0003053	72.20	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	72.11	silver quality
granulocyte	CL:0000094	71.68	gold quality
primary visual cortex	UBERON:0002436	71.56	gold quality
cortical plate	UBERON:0005343	71.34	gold quality
superior frontal gyrus	UBERON:0002661	70.56	gold quality
minor salivary gland	UBERON:0001830	70.51	gold quality
esophagus mucosa	UBERON:0002469	70.50	gold quality
stromal cell of endometrium	CL:0002255	70.40	gold quality
saliva-secreting gland	UBERON:0001044	70.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.