FAM218A

Summary

FAM218A (family with sequence similarity 218 member A, HGNC:26466) is a long non-coding RNA gene on chromosome 4q32.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26466
Approved symbol	FAM218A
Name	family with sequence similarity 218 member A
Location	4q32.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ31659, TRIM61-AS1
Ensembl gene	ENSG00000250486
Ensembl biotype	lncRNA
Entrez	152756
RNAcentral	URS0000E60AFE — lncRNA, 2184 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000648094

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000648094 — 1 exons

Exon	Start	End
ENSE00004069019	164956946	164959122

Expression profiles

Bgee: expression breadth ubiquitous, 172 present calls, max score 88.56.

FANTOM5 (CAGE): breadth broad, TPM avg 1.7211 / max 38.0199, expressed in 761 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
50428	1.3563	655
50427	0.3648	213

Top tissues by expression

235 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.56	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.56	gold quality
cortical plate	UBERON:0005343	76.30	gold quality
ganglionic eminence	UBERON:0004023	72.26	gold quality
ventricular zone	UBERON:0003053	70.54	gold quality
endothelial cell	CL:0000115	69.59	gold quality
sural nerve	UBERON:0015488	69.57	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	68.39	gold quality
cerebellar hemisphere	UBERON:0002245	68.25	gold quality
cerebellar cortex	UBERON:0002129	68.16	gold quality
right hemisphere of cerebellum	UBERON:0014890	67.87	gold quality
cerebellum	UBERON:0002037	67.09	gold quality
adenohypophysis	UBERON:0002196	66.99	gold quality
tibial nerve	UBERON:0001323	66.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	66.55	gold quality
left lobe of thyroid gland	UBERON:0001120	66.51	gold quality
oviduct epithelium	UBERON:0004804	66.44	gold quality
thyroid gland	UBERON:0002046	66.40	gold quality
spinal cord	UBERON:0002240	66.15	gold quality
hypothalamus	UBERON:0001898	65.82	gold quality
pituitary gland	UBERON:0000007	65.80	gold quality
nucleus accumbens	UBERON:0001882	65.72	gold quality
right lobe of thyroid gland	UBERON:0001119	65.67	gold quality
anterior cingulate cortex	UBERON:0009835	65.40	gold quality
corpus callosum	UBERON:0002336	64.69	gold quality
left testis	UBERON:0004533	64.35	gold quality
right frontal lobe	UBERON:0002810	64.33	gold quality
calcaneal tendon	UBERON:0003701	64.16	gold quality
pigmented layer of retina	UBERON:0001782	64.13	gold quality
caudate nucleus	UBERON:0001873	64.04	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.05

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.