FAM223A

Summary

FAM223A (family with sequence similarity 223 member A, HGNC:30612) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:30612
Approved symbol	FAM223A
Name	family with sequence similarity 223 member A
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Aliases	SPCX
Ensembl gene	ENSG00000279245
Ensembl biotype	lncRNA
Entrez	100132967
RNAcentral	URS000075CB6D — lncRNA, 713 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000625204

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625204 — 1 exons

Exon	Start	End
ENSE00003757863	154571248	154571960

Expression profiles

Bgee: expression breadth ubiquitous, 123 present calls, max score 86.44.

Top tissues by expression

123 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.44	gold quality
granulocyte	CL:0000094	74.35	gold quality
mucosa of transverse colon	UBERON:0004991	72.13	gold quality
blood	UBERON:0000178	71.86	gold quality
lower esophagus mucosa	UBERON:0035834	71.53	gold quality
right lobe of liver	UBERON:0001114	70.84	gold quality
spleen	UBERON:0002106	70.83	gold quality
right coronary artery	UBERON:0001625	68.77	gold quality
leukocyte	CL:0000738	67.67	gold quality
mucosa of stomach	UBERON:0001199	67.57	gold quality
left uterine tube	UBERON:0001303	67.41	gold quality
monocyte	CL:0000576	66.78	gold quality
tibial artery	UBERON:0007610	66.06	gold quality
popliteal artery	UBERON:0002250	65.93	gold quality
liver	UBERON:0002107	65.90	gold quality
adenohypophysis	UBERON:0002196	65.68	gold quality
urinary bladder	UBERON:0001255	65.19	gold quality
right lung	UBERON:0002167	65.11	gold quality
thoracic aorta	UBERON:0001515	65.10	gold quality
muscle layer of sigmoid colon	UBERON:0035805	64.82	gold quality
ascending aorta	UBERON:0001496	64.81	gold quality
lower esophagus	UBERON:0013473	64.62	gold quality
descending thoracic aorta	UBERON:0002345	64.61	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.60	gold quality
metanephros cortex	UBERON:0010533	64.49	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	64.26	gold quality
fundus of stomach	UBERON:0001160	64.18	gold quality
ectocervix	UBERON:0012249	64.07	gold quality
cortical plate	UBERON:0005343	64.02	gold quality
skin of abdomen	UBERON:0001416	63.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.12

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Paralogs (1): FAM223B (ENSG00000272681)

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.