FAM226A

Summary

FAM226A (family with sequence similarity 226 member A, HGNC:28544) is a long non-coding RNA gene on chromosome Xq13.1.

At a glance

• GWAS associations: 1

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:28544
Approved symbol	FAM226A
Name	family with sequence similarity 226 member A
Location	Xq13.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	MGC34827
Entrez	203429
RNAcentral	URS000075D90C — lncRNA, 2023 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 299 via entrez): RS1197102905 (X:72944115 A>G), RS1198932721 (X:72943835 G>A,C), RS1202396970 (X:72943885 A>G), RS1212719177 (X:72943772 A>C,G), RS1229164919 (X:72943772 AAGGAGGAGGAGGAGGAGGAGG>A,AAGGAGGAGG,AAGGAGGAGGAGG,AAGGAGGAGGAGGAGG,AAGGAGGAGGAGGAGGAGG,AAGGAGGAGGAGGAGGAGGAGGAGG,AAGGAGGAGGAGGAGGAGGAGGAGGAGG,AAGGAGGAGGAGGAGGAGGAGGAGGAGGAGG), RS1273116988 (X:72944111 T>C), RS1305506799 (X:72943814 G>A,C), RS1395867526 (X:72943820 CAGGAGGAGGAGGAGG>C,CAGGAGGAGGAGGAGGAGG,CAGGAGGAGGAGGAGGAGGAGG,CAGGAGGAGGAGGAGGAGGAGGAGG,CAGGAGGAGGAGGAGGAGGAGGAGGAGGAGG,CAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGGAGG), RS1404761963 (X:72943805 C>A,G), RS1437095902 (X:72944063 C>T), RS1470586027 (X:72943766 G>GGGAGAA), RS1480669199 (X:72943855 G>A,C), RS1556358211 (X:72941298 C>T), RS1556358213 (X:72941311 C>T), RS1556358215 (X:72941336 C>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

1 associations (top):

Study	Trait	p-value
GCST008103_139	Bipolar disorder	3.000000e-06

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.