FAM226B

Summary

FAM226B (family with sequence similarity 226 member B, HGNC:31964) is a long non-coding RNA gene on chromosome Xq13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31964
Approved symbol	FAM226B
Name	family with sequence similarity 226 member B
Location	Xq13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000269911
Ensembl biotype	lncRNA
Entrez	653687
RNAcentral	URS0000759EE9 — lncRNA, 2096 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000602508

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000602508 — 1 exons

Exon	Start	End
ENSE00003321976	72777608	72779097

Expression profiles

Bgee: expression breadth ubiquitous, 188 present calls, max score 86.91.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	86.91	gold quality
cerebellar hemisphere	UBERON:0002245	86.78	gold quality
cerebellar cortex	UBERON:0002129	86.56	gold quality
cerebellum	UBERON:0002037	85.76	gold quality
thymus	UBERON:0002370	83.95	gold quality
endothelial cell	CL:0000115	82.30	gold quality
primary visual cortex	UBERON:0002436	81.67	gold quality
adenohypophysis	UBERON:0002196	81.62	gold quality
pituitary gland	UBERON:0000007	81.50	gold quality
Brodmann (1909) area 23	UBERON:0013554	81.24	gold quality
middle temporal gyrus	UBERON:0002771	77.29	silver quality
right frontal lobe	UBERON:0002810	76.83	gold quality
cortical plate	UBERON:0005343	75.91	gold quality
anterior cingulate cortex	UBERON:0009835	75.85	gold quality
left ovary	UBERON:0002119	75.35	gold quality
ganglionic eminence	UBERON:0004023	74.94	gold quality
occipital lobe	UBERON:0002021	74.92	gold quality
hypothalamus	UBERON:0001898	74.89	gold quality
Brodmann (1909) area 9	UBERON:0013540	74.70	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	74.36	gold quality
left lobe of thyroid gland	UBERON:0001120	74.28	gold quality
right ovary	UBERON:0002118	74.11	gold quality
lymph node	UBERON:0000029	73.99	gold quality
right lobe of thyroid gland	UBERON:0001119	73.94	gold quality
thyroid gland	UBERON:0002046	73.85	gold quality
neocortex	UBERON:0001950	73.50	gold quality
spleen	UBERON:0002106	73.38	gold quality
cerebellar vermis	UBERON:0004720	73.34	gold quality
ventricular zone	UBERON:0003053	73.22	gold quality
brain	UBERON:0000955	73.19	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.