FAM230A

Summary

FAM230A (family with sequence similarity 230 member A, HGNC:45045) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45045
Approved symbol	FAM230A
Name	family with sequence similarity 230 member A
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	DGCR15
Ensembl gene	ENSG00000277870
Ensembl biotype	lncRNA
Entrez	653203
RNAcentral	URS0000DBA62F — lncRNA, 3186 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000615181, ENST00000624001, ENST00000624459, ENST00000736264, ENST00000736265, ENST00000833017, ENST00000833018, ENST00000833019, ENST00000833020, ENST00000833021, ENST00000833022, ENST00000833023

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000615181 — 3 exons

Exon	Start	End
ENSE00003712582	18487126	18487204
ENSE00003717916	18489205	18489266
ENSE00003738260	18489732	18489905

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 84.66.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	84.66	gold quality
right testis	UBERON:0004534	84.03	gold quality
testis	UBERON:0000473	83.63	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.87	gold quality
sural nerve	UBERON:0015488	78.57	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	73.08	gold quality
adult mammalian kidney	UBERON:0000082	59.55	gold quality
multicellular organism	UBERON:0000468	58.81	gold quality
kidney	UBERON:0002113	57.36	gold quality
monocyte	CL:0000576	56.14	gold quality
islet of Langerhans	UBERON:0000006	55.41	gold quality
blood	UBERON:0000178	54.57	gold quality
pancreas	UBERON:0001264	53.42	gold quality
placenta	UBERON:0001987	52.91	silver quality
tibial nerve	UBERON:0001323	52.51	gold quality
prefrontal cortex	UBERON:0000451	51.53	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	51.43	gold quality
body of pancreas	UBERON:0001150	51.23	gold quality
liver	UBERON:0002107	51.22	silver quality
bone marrow	UBERON:0002371	50.15	silver quality
muscle of leg	UBERON:0001383	49.60	gold quality
right lobe of liver	UBERON:0001114	49.37	silver quality
gastrocnemius	UBERON:0001388	48.46	gold quality
small intestine	UBERON:0002108	48.18	gold quality
right coronary artery	UBERON:0001625	47.93	gold quality
omental fat pad	UBERON:0010414	47.88	gold quality
lower esophagus muscularis layer	UBERON:0035833	47.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.23	gold quality
adipose tissue	UBERON:0001013	47.16	gold quality
cerebellar cortex	UBERON:0002129	46.92	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.48

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.