FAM230C

Summary

FAM230C (family with sequence similarity 230 member C, HGNC:24482) is a long non-coding RNA gene on chromosome 13q11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:24482
Approved symbol	FAM230C
Name	family with sequence similarity 230 member C
Location	13q11
Locus type	RNA, long non-coding
Status	Approved
Aliases	DKFZP434B061
Ensembl gene	ENSG00000279516
Ensembl biotype	lncRNA
Entrez	26080
RNAcentral	URS000075EAC5 — lncRNA, 1962 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 33 — 33 lncRNA

ENST00000623511, ENST00000651051, ENST00000651377, ENST00000791216, ENST00000791217, ENST00000791218, ENST00000791219, ENST00000791220, ENST00000791221, ENST00000791222, ENST00000791223, ENST00000791224, ENST00000791225, ENST00000791226, ENST00000791227, ENST00000791228, ENST00000791229, ENST00000791230, ENST00000791231, ENST00000791232, ENST00000791233, ENST00000791234, ENST00000791235, ENST00000791236, ENST00000791237, ENST00000791238, ENST00000791239, ENST00000791240, ENST00000791241, ENST00000791242, ENST00000791243, ENST00000791244, ENST00000791245

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000623511 — 8 exons

Exon	Start	End
ENSE00003756305	18222495	18222581
ENSE00003756406	18229547	18229608
ENSE00003757389	18227479	18227544
ENSE00003757767	18230503	18232024
ENSE00003757855	18218999	18219057
ENSE00003758598	18195297	18195411
ENSE00003758718	18219526	18219550
ENSE00003759256	18230074	18230107

Expression profiles

Bgee: expression breadth broad, 74 present calls, max score 88.55.

Top tissues by expression

74 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.55	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.01	gold quality
left testis	UBERON:0004533	66.31	gold quality
testis	UBERON:0000473	66.25	gold quality
right testis	UBERON:0004534	66.14	gold quality
monocyte	CL:0000576	62.98	gold quality
leukocyte	CL:0000738	62.79	gold quality
ganglionic eminence	UBERON:0004023	58.20	silver quality
ventricular zone	UBERON:0003053	57.41	silver quality
cortex of kidney	UBERON:0001225	55.37	gold quality
endometrium	UBERON:0001295	54.86	gold quality
blood	UBERON:0000178	54.40	gold quality
multicellular organism	UBERON:0000468	53.80	gold quality
bone marrow	UBERON:0002371	53.40	silver quality
kidney	UBERON:0002113	52.14	gold quality
adult mammalian kidney	UBERON:0000082	50.54	gold quality
stomach	UBERON:0000945	49.78	gold quality
body of stomach	UBERON:0001161	49.53	gold quality
prefrontal cortex	UBERON:0000451	48.74	silver quality
vermiform appendix	UBERON:0001154	48.31	gold quality
fundus of stomach	UBERON:0001160	47.72	gold quality
gastrocnemius	UBERON:0001388	46.35	gold quality
placenta	UBERON:0001987	46.29	gold quality
islet of Langerhans	UBERON:0000006	46.06	silver quality
body of pancreas	UBERON:0001150	45.03	silver quality
right atrium auricular region	UBERON:0006631	44.48	silver quality
spleen	UBERON:0002106	42.99	silver quality
superior frontal gyrus	UBERON:0002661	42.98	silver quality
cerebral cortex	UBERON:0000956	42.96	silver quality
tibial nerve	UBERON:0001323	42.73	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.33

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• FAM230C contains copies of the DNA translocation breakpoint/AT-rich sequence. (PMID:29668722)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.