FAM230D

Summary

FAM230D (family with sequence similarity 230 member D, HGNC:53910) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53910
Approved symbol	FAM230D
Name	family with sequence similarity 230 member D
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC008079.1
Ensembl gene	ENSG00000187979
Ensembl biotype	lncRNA
Entrez	100996415
RNAcentral	URS0001980E2B — lncRNA, 2984 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 21 — 21 lncRNA

ENST00000434390, ENST00000833192, ENST00000833193, ENST00000833194, ENST00000833195, ENST00000833196, ENST00000833197, ENST00000833198, ENST00000833199, ENST00000833200, ENST00000833201, ENST00000833202, ENST00000833203, ENST00000833204, ENST00000833205, ENST00000833206, ENST00000833207, ENST00000833208, ENST00000833209, ENST00000833210, ENST00000833211

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434390 — 9 exons

Exon	Start	End
ENSE00001721880	18205775	18205915
ENSE00001766364	18178038	18178465
ENSE00003289339	18191183	18191248
ENSE00003295032	18199683	18199741
ENSE00003311745	18188623	18188656
ENSE00003398880	18189122	18189183
ENSE00003429735	18199190	18199214
ENSE00003454115	18196157	18196243
ENSE00003455116	18183110	18184066

Expression profiles

Bgee: expression breadth broad, 35 present calls, max score 89.43.

Top tissues by expression

35 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.43	gold quality
right testis	UBERON:0004534	84.36	gold quality
left testis	UBERON:0004533	84.31	gold quality
testis	UBERON:0000473	83.35	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.61	silver quality
stomach	UBERON:0000945	68.01	silver quality
multicellular organism	UBERON:0000468	67.83	gold quality
tibial nerve	UBERON:0001323	63.72	gold quality
prefrontal cortex	UBERON:0000451	53.44	silver quality
monocyte	CL:0000576	50.10	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	49.88	gold quality
gastrocnemius	UBERON:0001388	49.62	gold quality
cerebellar hemisphere	UBERON:0002245	49.13	silver quality
Brodmann (1909) area 9	UBERON:0013540	48.47	silver quality
tibial artery	UBERON:0007610	48.07	gold quality
adenohypophysis	UBERON:0002196	47.37	gold quality
pituitary gland	UBERON:0000007	46.75	gold quality
Ammon’s horn	UBERON:0001954	46.10	gold quality
right lobe of liver	UBERON:0001114	43.40	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	43.37	gold quality
subcutaneous adipose tissue	UBERON:0002190	43.35	gold quality
thyroid gland	UBERON:0002046	42.83	silver quality
left lobe of thyroid gland	UBERON:0001120	42.74	gold quality
right hemisphere of cerebellum	UBERON:0014890	42.50	silver quality
lower esophagus muscularis layer	UBERON:0035833	42.27	gold quality
anterior cingulate cortex	UBERON:0009835	42.15	gold quality
skin of leg	UBERON:0001511	40.93	gold quality
amygdala	UBERON:0001876	39.46	silver quality
right atrium auricular region	UBERON:0006631	38.52	silver quality
right frontal lobe	UBERON:0002810	38.31	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.