FAM230E

Summary

FAM230E (family with sequence similarity 230 member E, HGNC:52450) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52450
Approved symbol	FAM230E
Name	family with sequence similarity 230 member E
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000182824
Ensembl biotype	lncRNA
Entrez	642643
RNAcentral	URS0001981295 — lncRNA, 1849 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000342888, ENST00000611876, ENST00000753579, ENST00000753580, ENST00000753581, ENST00000753582, ENST00000753583, ENST00000753584, ENST00000753585, ENST00000753586, ENST00000753587

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000342888 — 9 exons

Exon	Start	End
ENSE00001596564	18736032	18736090
ENSE00001608479	18757467	18757894
ENSE00001642671	18751869	18752825
ENSE00001670476	18739530	18739616
ENSE00001693656	18746574	18746635
ENSE00001729746	18744510	18744575
ENSE00001744915	18747101	18747134
ENSE00001763149	18736559	18736583
ENSE00002220770	18733914	18734054

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 88.77.

Top tissues by expression

100 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.77	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.33	gold quality
right testis	UBERON:0004534	84.17	gold quality
left testis	UBERON:0004533	84.16	gold quality
testis	UBERON:0000473	83.08	gold quality
cortical plate	UBERON:0005343	63.19	gold quality
mucosa of transverse colon	UBERON:0004991	61.26	gold quality
pituitary gland	UBERON:0000007	58.91	gold quality
adenohypophysis	UBERON:0002196	57.22	gold quality
right lobe of liver	UBERON:0001114	56.82	gold quality
myometrium	UBERON:0001296	56.48	gold quality
monocyte	CL:0000576	55.76	gold quality
bone marrow	UBERON:0002371	55.51	silver quality
body of stomach	UBERON:0001161	55.48	gold quality
stomach	UBERON:0000945	55.07	gold quality
blood	UBERON:0000178	54.14	silver quality
lymph node	UBERON:0000029	53.83	gold quality
liver	UBERON:0002107	53.56	gold quality
endometrium	UBERON:0001295	52.49	gold quality
right ovary	UBERON:0002118	52.33	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.03	gold quality
fundus of stomach	UBERON:0001160	51.97	gold quality
prefrontal cortex	UBERON:0000451	51.87	gold quality
ovary	UBERON:0000992	51.40	gold quality
left ovary	UBERON:0002119	51.18	gold quality
adult mammalian kidney	UBERON:0000082	51.15	gold quality
multicellular organism	UBERON:0000468	50.98	gold quality
islet of Langerhans	UBERON:0000006	50.65	gold quality
kidney	UBERON:0002113	49.84	gold quality
pancreas	UBERON:0001264	48.17	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.