FAM230G

Summary

FAM230G (family with sequence similarity 230 member G, HGNC:52423) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52423
Approved symbol	FAM230G
Name	family with sequence similarity 230 member G
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC007731.1
Ensembl gene	ENSG00000188280
Ensembl biotype	lncRNA
Entrez	101927859
RNAcentral	URS0001980EAA — lncRNA, 818 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000583722, ENST00000610338, ENST00000617303, ENST00000844019, ENST00000844020, ENST00000844021, ENST00000844022, ENST00000844023, ENST00000844024, ENST00000844025, ENST00000844026, ENST00000844027

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000583722 — 6 exons

Exon	Start	End
ENSE00001883961	20349486	20349551
ENSE00002230102	20351555	20351616
ENSE00002727656	20352082	20352255
ENSE00003717169	20341524	20341548
ENSE00003717757	20340996	20341055
ENSE00003727132	20344494	20344580

Expression profiles

Bgee: expression breadth broad, 80 present calls, max score 86.46.

Top tissues by expression

80 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.46	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	77.55	gold quality
left testis	UBERON:0004533	71.50	gold quality
testis	UBERON:0000473	70.78	gold quality
right testis	UBERON:0004534	70.44	gold quality
ganglionic eminence	UBERON:0004023	58.09	silver quality
skeletal muscle tissue	UBERON:0001134	56.83	silver quality
adrenal tissue	UBERON:0018303	56.57	gold quality
multicellular organism	UBERON:0000468	55.88	gold quality
hindlimb stylopod muscle	UBERON:0004252	53.98	silver quality
endometrium	UBERON:0001295	53.61	silver quality
blood	UBERON:0000178	53.16	gold quality
lymph node	UBERON:0000029	52.22	gold quality
prefrontal cortex	UBERON:0000451	51.55	silver quality
islet of Langerhans	UBERON:0000006	51.05	gold quality
monocyte	CL:0000576	50.88	silver quality
Ammon’s horn	UBERON:0001954	50.70	gold quality
cortex of kidney	UBERON:0001225	49.95	gold quality
adrenal gland	UBERON:0002369	49.90	gold quality
temporal lobe	UBERON:0001871	48.11	gold quality
gastrocnemius	UBERON:0001388	47.99	gold quality
right atrium auricular region	UBERON:0006631	47.63	gold quality
small intestine	UBERON:0002108	47.40	gold quality
pancreas	UBERON:0001264	46.64	gold quality
left adrenal gland	UBERON:0001234	46.09	gold quality
intestine	UBERON:0000160	44.94	gold quality
amygdala	UBERON:0001876	44.88	gold quality
body of pancreas	UBERON:0001150	44.76	silver quality
vermiform appendix	UBERON:0001154	44.63	silver quality
stomach	UBERON:0000945	44.56	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.