FAM230H

Summary

FAM230H (family with sequence similarity 230 member H, HGNC:53977) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53977
Approved symbol	FAM230H
Name	family with sequence similarity 230 member H
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	AP000552.1
Ensembl gene	ENSG00000206142
Ensembl biotype	lncRNA
Entrez	100996335
RNAcentral	URS0001980F45 — lncRNA, 3106 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 16 — 16 lncRNA

ENST00000411581, ENST00000416405, ENST00000416615, ENST00000431488, ENST00000436681, ENST00000447720, ENST00000451574, ENST00000452952, ENST00000453273, ENST00000731567, ENST00000731568, ENST00000790953, ENST00000790954, ENST00000790955, ENST00000790956, ENST00000790957

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000411581 — 3 exons

Exon	Start	End
ENSE00001750614	21322796	21322984
ENSE00004171697	21326533	21326636
ENSE00004171699	21322141	21322327

Expression profiles

Bgee: expression breadth broad, 61 present calls, max score 85.01.

Top tissues by expression

61 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.01	gold quality
left testis	UBERON:0004533	84.64	gold quality
testis	UBERON:0000473	83.82	gold quality
right testis	UBERON:0004534	82.92	gold quality
lung	UBERON:0002048	61.31	gold quality
multicellular organism	UBERON:0000468	60.36	gold quality
heart left ventricle	UBERON:0002084	55.67	gold quality
islet of Langerhans	UBERON:0000006	55.32	gold quality
monocyte	CL:0000576	53.60	gold quality
blood	UBERON:0000178	52.69	gold quality
prefrontal cortex	UBERON:0000451	51.84	silver quality
tibial nerve	UBERON:0001323	50.74	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.72	gold quality
left adrenal gland	UBERON:0001234	48.77	gold quality
superior frontal gyrus	UBERON:0002661	48.39	gold quality
frontal cortex	UBERON:0001870	47.46	gold quality
stomach	UBERON:0000945	47.37	gold quality
subcutaneous adipose tissue	UBERON:0002190	47.33	gold quality
cerebellar hemisphere	UBERON:0002245	46.97	silver quality
body of stomach	UBERON:0001161	46.94	gold quality
endometrium	UBERON:0001295	46.82	silver quality
gastrocnemius	UBERON:0001388	46.75	gold quality
tibial artery	UBERON:0007610	46.34	silver quality
adenohypophysis	UBERON:0002196	45.67	gold quality
lymph node	UBERON:0000029	44.52	silver quality
fallopian tube	UBERON:0003889	44.30	gold quality
ovary	UBERON:0000992	43.98	silver quality
brain	UBERON:0000955	43.65	gold quality
right hemisphere of cerebellum	UBERON:0014890	43.13	silver quality
pituitary gland	UBERON:0000007	43.12	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.