FAM230I

Summary

FAM230I (family with sequence similarity 230 member I, HGNC:52446) is a long non-coding RNA gene on chromosome 22q11.23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52446
Approved symbol	FAM230I
Name	family with sequence similarity 230 member I
Location	22q11.23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000178248
Ensembl biotype	lncRNA
Entrez	388882
RNAcentral	URS000076148F — lncRNA, 1578 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 44 — 44 lncRNA

ENST00000320372, ENST00000785831, ENST00000785832, ENST00000785833, ENST00000785834, ENST00000785835, ENST00000785836, ENST00000785837, ENST00000785838, ENST00000785839, ENST00000785840, ENST00000785841, ENST00000785842, ENST00000785843, ENST00000785844, ENST00000785845, ENST00000785846, ENST00000785847, ENST00000785848, ENST00000785849, ENST00000785850, ENST00000785851, ENST00000785852, ENST00000785853, ENST00000785854, ENST00000785855, ENST00000785856, ENST00000785857, ENST00000785858, ENST00000785859, ENST00000785860, ENST00000785861, ENST00000785862, ENST00000785863, ENST00000785864, ENST00000785865, ENST00000785866, ENST00000785867, ENST00000785868, ENST00000785869, ENST00000785870, ENST00000785871, ENST00000785872, ENST00000785873

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000320372 — 12 exons

Exon	Start	End
ENSE00001280542	23469996	23470037
ENSE00001378654	23486879	23486980
ENSE00001432676	23467275	23467316
ENSE00001433271	23462086	23462678
ENSE00001434467	23469337	23469487
ENSE00003460336	23480417	23480500
ENSE00003493698	23470315	23470336
ENSE00003549645	23473378	23473411
ENSE00003599827	23473877	23473938
ENSE00003622042	23470808	23471163
ENSE00003634277	23482575	23482605
ENSE00003687953	23483068	23483126

Expression profiles

Bgee: expression breadth broad, 99 present calls, max score 84.23.

Top tissues by expression

99 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.23	gold quality
right testis	UBERON:0004534	79.77	gold quality
left testis	UBERON:0004533	79.27	gold quality
testis	UBERON:0000473	78.73	gold quality
pituitary gland	UBERON:0000007	61.36	gold quality
sural nerve	UBERON:0015488	61.33	silver quality
mucosa of transverse colon	UBERON:0004991	61.04	gold quality
ventricular zone	UBERON:0003053	59.85	silver quality
adenohypophysis	UBERON:0002196	59.49	gold quality
cortical plate	UBERON:0005343	58.82	silver quality
ganglionic eminence	UBERON:0004023	56.92	silver quality
left ovary	UBERON:0002119	56.72	gold quality
right adrenal gland	UBERON:0001233	56.43	gold quality
hypothalamus	UBERON:0001898	56.41	gold quality
ovary	UBERON:0000992	55.78	gold quality
prostate gland	UBERON:0002367	54.02	gold quality
placenta	UBERON:0001987	53.34	gold quality
right ovary	UBERON:0002118	51.64	gold quality
skeletal muscle tissue	UBERON:0001134	51.54	silver quality
multicellular organism	UBERON:0000468	51.52	gold quality
gastrocnemius	UBERON:0001388	51.40	gold quality
adult mammalian kidney	UBERON:0000082	51.05	gold quality
islet of Langerhans	UBERON:0000006	50.70	gold quality
right uterine tube	UBERON:0001302	50.41	gold quality
rectum	UBERON:0001052	49.78	gold quality
monocyte	CL:0000576	49.71	silver quality
endometrium	UBERON:0001295	49.69	gold quality
kidney	UBERON:0002113	49.56	gold quality
small intestine	UBERON:0002108	49.35	gold quality
small intestine Peyer’s patch	UBERON:0003454	48.93	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.