FAM230J

Summary

FAM230J (family with sequence similarity 230 member J, HGNC:52448) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:52448
Approved symbol	FAM230J
Name	family with sequence similarity 230 member J
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000274044
Ensembl biotype	lncRNA
Entrez	729461
RNAcentral	URS0001980F1F — lncRNA, 1901 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000613790, ENST00000615974, ENST00000618517, ENST00000619172, ENST00000833533

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000613790 — 8 exons

Exon	Start	End
ENSE00003718833	18370585	18370713
ENSE00003719347	18383487	18383511
ENSE00003719912	18386386	18386480
ENSE00003723471	18372923	18372956
ENSE00003730153	18383980	18384038
ENSE00003748957	18375484	18375549
ENSE00003750546	18373422	18373483
ENSE00003754029	18380456	18380542

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 82.38.

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.38	gold quality
right testis	UBERON:0004534	80.13	gold quality
left testis	UBERON:0004533	79.93	gold quality
testis	UBERON:0000473	79.64	gold quality
multicellular organism	UBERON:0000468	62.24	gold quality
ovary	UBERON:0000992	58.27	gold quality
blood	UBERON:0000178	52.67	gold quality
superior frontal gyrus	UBERON:0002661	52.17	gold quality
gastrocnemius	UBERON:0001388	49.33	gold quality
monocyte	CL:0000576	48.39	silver quality
kidney	UBERON:0002113	47.09	gold quality
urinary bladder	UBERON:0001255	46.70	gold quality
small intestine	UBERON:0002108	46.70	gold quality
adult mammalian kidney	UBERON:0000082	46.42	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	45.69	silver quality
left adrenal gland cortex	UBERON:0035825	45.49	gold quality
body of stomach	UBERON:0001161	45.32	gold quality
muscle layer of sigmoid colon	UBERON:0035805	45.08	gold quality
cerebellar cortex	UBERON:0002129	45.07	silver quality
tibial nerve	UBERON:0001323	44.78	gold quality
stomach	UBERON:0000945	44.75	gold quality
frontal cortex	UBERON:0001870	44.72	gold quality
body of pancreas	UBERON:0001150	44.23	silver quality
heart	UBERON:0000948	44.17	silver quality
cerebellar hemisphere	UBERON:0002245	44.17	silver quality
subcutaneous adipose tissue	UBERON:0002190	44.00	gold quality
thoracic mammary gland	UBERON:0005200	43.48	gold quality
prostate gland	UBERON:0002367	43.14	gold quality
Ammon’s horn	UBERON:0001954	43.06	gold quality
skin of leg	UBERON:0001511	42.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.