FAM239B

Summary

FAM239B (family with sequence similarity 239 member B, HGNC:53415) is a long non-coding RNA gene on chromosome Xp22.33.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53415
Approved symbol	FAM239B
Name	family with sequence similarity 239 member B
Location	Xp22.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205663
Entrez	729162

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1027190063 (X:3914931 G>C,T), RS1044739736 (X:3905311 AG>A), RS1050049799 (X:3886717 G>C), RS1052311123 (X:3886853 G>A), RS1054510 (X:3892934 C>T), RS111612277 (X:3921990 T>A), RS112141949 (X:3892958 T>A), RS112536224 (X:3892955 C>T), RS1157225001 (X:3905031 G>A), RS1157283941 (X:3900877 C>T), RS1157599958 (X:3893096 C>T), RS1157925538 (X:3892701 T>C), RS1158045599 (X:3914674 T>C), RS1160105362 (X:3907106 A>T), RS1160289498 (X:3902919 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.