FAM245A

Summary

FAM245A (family with sequence similarity 245 member A, HGNC:45163) is a long non-coding RNA gene on chromosome 10q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45163
Approved symbol	FAM245A
Name	family with sequence similarity 245 member A
Location	10q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228055
Ensembl biotype	lncRNA
Entrez	728218
RNAcentral	URS0000759B6F — lncRNA, 1195 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 17 — 17 lncRNA

ENST00000429129, ENST00000447936, ENST00000656643, ENST00000662339, ENST00000665232, ENST00000670136, ENST00000819503, ENST00000819504, ENST00000819505, ENST00000819506, ENST00000819507, ENST00000819508, ENST00000819509, ENST00000819510, ENST00000819511, ENST00000819512, ENST00000819513

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000429129 — 3 exons

Exon	Start	End
ENSE00002443430	87398020	87398200
ENSE00004224486	87396564	87397389
ENSE00004224493	87407503	87408375

Expression profiles

Bgee: expression breadth ubiquitous, 108 present calls, max score 78.28.

Top tissues by expression

108 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.28	silver quality
adult mammalian kidney	UBERON:0000082	75.22	gold quality
kidney	UBERON:0002113	72.46	gold quality
liver	UBERON:0002107	68.55	gold quality
right lobe of liver	UBERON:0001114	67.86	gold quality
metanephros cortex	UBERON:0010533	67.45	gold quality
ventricular zone	UBERON:0003053	66.59	gold quality
cortical plate	UBERON:0005343	65.92	gold quality
cortex of kidney	UBERON:0001225	65.23	gold quality
colonic epithelium	UBERON:0000397	64.08	silver quality
bone marrow cell	CL:0002092	63.05	silver quality
body of pancreas	UBERON:0001150	62.84	gold quality
pancreas	UBERON:0001264	61.21	gold quality
gall bladder	UBERON:0002110	59.53	gold quality
ganglionic eminence	UBERON:0004023	56.90	gold quality
monocyte	CL:0000576	56.14	gold quality
bone marrow	UBERON:0002371	54.27	silver quality
blood	UBERON:0000178	53.09	gold quality
lymph node	UBERON:0000029	52.79	gold quality
islet of Langerhans	UBERON:0000006	52.74	gold quality
corpus callosum	UBERON:0002336	52.67	silver quality
duodenum	UBERON:0002114	52.06	gold quality
adrenal tissue	UBERON:0018303	51.49	gold quality
hindlimb stylopod muscle	UBERON:0004252	50.47	silver quality
nucleus accumbens	UBERON:0001882	48.92	gold quality
calcaneal tendon	UBERON:0003701	48.22	silver quality
prefrontal cortex	UBERON:0000451	47.45	silver quality
myometrium	UBERON:0001296	47.22	gold quality
muscle of leg	UBERON:0001383	47.15	gold quality
gastrocnemius	UBERON:0001388	46.75	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.