FAM245B

Summary

FAM245B (family with sequence similarity 245 member B, HGNC:54133) is a long non-coding RNA gene on chromosome 10q11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54133
Approved symbol	FAM245B
Name	family with sequence similarity 245 member B
Location	10q11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285662
Ensembl biotype	lncRNA
Entrez	102724643
RNAcentral	URS0000DB7FB3 — lncRNA, 1199 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000626319, ENST00000628708, ENST00000649270, ENST00000655955, ENST00000661138, ENST00000716494, ENST00000716495, ENST00000716496, ENST00000716541, ENST00000716542

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000626319 — 4 exons

Exon	Start	End
ENSE00003763353	46759054	46759740
ENSE00003774757	46756991	46757150
ENSE00004029926	46758834	46758953
ENSE00004029927	46758078	46758214

Expression profiles

Bgee: expression breadth ubiquitous, 103 present calls, max score 81.94.

Top tissues by expression

103 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.94	gold quality
adult mammalian kidney	UBERON:0000082	71.30	gold quality
liver	UBERON:0002107	69.72	gold quality
kidney	UBERON:0002113	69.21	gold quality
right lobe of liver	UBERON:0001114	66.79	gold quality
skeletal muscle tissue	UBERON:0001134	64.61	gold quality
muscle tissue	UBERON:0002385	62.20	gold quality
urinary bladder	UBERON:0001255	59.08	gold quality
cortical plate	UBERON:0005343	58.84	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.57	silver quality
cortex of kidney	UBERON:0001225	58.43	gold quality
monocyte	CL:0000576	57.54	gold quality
ganglionic eminence	UBERON:0004023	56.92	gold quality
bone marrow	UBERON:0002371	55.02	gold quality
muscle of leg	UBERON:0001383	54.34	gold quality
blood	UBERON:0000178	53.28	gold quality
metanephros cortex	UBERON:0010533	52.07	gold quality
lymph node	UBERON:0000029	51.52	gold quality
islet of Langerhans	UBERON:0000006	51.48	gold quality
duodenum	UBERON:0002114	51.46	gold quality
stromal cell of endometrium	CL:0002255	50.78	silver quality
testis	UBERON:0000473	49.82	silver quality
gall bladder	UBERON:0002110	49.71	gold quality
superior frontal gyrus	UBERON:0002661	49.57	gold quality
prefrontal cortex	UBERON:0000451	48.93	silver quality
pancreas	UBERON:0001264	48.47	gold quality
gastrocnemius	UBERON:0001388	47.75	silver quality
placenta	UBERON:0001987	47.37	gold quality
multicellular organism	UBERON:0000468	47.29	gold quality
nucleus accumbens	UBERON:0001882	46.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.