FAM247B

Summary

FAM247B (family with sequence similarity 247 member B, HGNC:54927) is a long non-coding RNA gene on chromosome 22q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54927
Approved symbol	FAM247B
Name	family with sequence similarity 247 member B
Location	22q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000278044
Ensembl biotype	lncRNA
Entrez	117751732
RNAcentral	URS00026A2467 — lncRNA, 1165 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000621762, ENST00000843179, ENST00000843180

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000621762 — 2 exons

Exon	Start	End
ENSE00004268995	18501221	18501849
ENSE00004268997	18511886	18512497

Expression profiles

Bgee: expression breadth broad, 56 present calls, max score 87.09.

Top tissues by expression

56 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.09	silver quality
cortical plate	UBERON:0005343	68.19	gold quality
urinary bladder	UBERON:0001255	64.20	silver quality
left adrenal gland cortex	UBERON:0035825	57.69	gold quality
left adrenal gland	UBERON:0001234	56.10	gold quality
adrenal gland	UBERON:0002369	54.48	gold quality
liver	UBERON:0002107	53.62	gold quality
placenta	UBERON:0001987	52.75	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.02	gold quality
skin of leg	UBERON:0001511	51.22	gold quality
muscle of leg	UBERON:0001383	50.98	gold quality
stomach	UBERON:0000945	50.57	silver quality
skin of abdomen	UBERON:0001416	49.05	gold quality
adenohypophysis	UBERON:0002196	49.03	gold quality
gastrocnemius	UBERON:0001388	49.00	gold quality
blood	UBERON:0000178	48.84	silver quality
heart left ventricle	UBERON:0002084	48.67	gold quality
cerebral cortex	UBERON:0000956	48.60	gold quality
right lobe of liver	UBERON:0001114	47.40	silver quality
multicellular organism	UBERON:0000468	47.11	gold quality
thyroid gland	UBERON:0002046	46.64	gold quality
cerebellar hemisphere	UBERON:0002245	46.45	silver quality
right lobe of thyroid gland	UBERON:0001119	46.34	gold quality
prefrontal cortex	UBERON:0000451	46.33	silver quality
right atrium auricular region	UBERON:0006631	46.30	gold quality
adult mammalian kidney	UBERON:0000082	46.19	gold quality
left lobe of thyroid gland	UBERON:0001120	45.91	gold quality
endometrium	UBERON:0001295	45.25	gold quality
transverse colon	UBERON:0001157	45.14	silver quality
left coronary artery	UBERON:0001626	45.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.