FAM27B

Summary

FAM27B (family with sequence similarity 27 member B, HGNC:23667) is a long non-coding RNA gene on chromosome 9q21.11.

At a glance

• Gene type: non-coding (transcribed_processed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23667
Approved symbol	FAM27B
Name	family with sequence similarity 27 member B
Location	9q21.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA12A20.3, FAM27A2
Ensembl gene	ENSG00000278763
Ensembl biotype	transcribed_processed_pseudogene
Entrez	100133121
RNAcentral	URS000075BE29 — lncRNA, 703 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_processed_pseudogene

ENST00000610601

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000610601 — 1 exons

Exon	Start	End
ENSE00003749302	67725690	67725902

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 86.20.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.20	silver quality
sural nerve	UBERON:0015488	85.59	gold quality
adenohypophysis	UBERON:0002196	83.69	gold quality
left testis	UBERON:0004533	82.97	gold quality
right testis	UBERON:0004534	82.27	gold quality
right uterine tube	UBERON:0001302	81.46	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.04	gold quality
pituitary gland	UBERON:0000007	80.36	gold quality
testis	UBERON:0000473	80.22	gold quality
ventricular zone	UBERON:0003053	78.79	gold quality
metanephros cortex	UBERON:0010533	75.55	gold quality
right coronary artery	UBERON:0001625	72.11	gold quality
mucosa of transverse colon	UBERON:0004991	70.78	gold quality
nucleus accumbens	UBERON:0001882	70.71	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.52	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.13	gold quality
cerebellar hemisphere	UBERON:0002245	68.77	gold quality
descending thoracic aorta	UBERON:0002345	68.14	gold quality
cerebellar cortex	UBERON:0002129	68.03	gold quality
islet of Langerhans	UBERON:0000006	67.82	gold quality
cerebellum	UBERON:0002037	67.54	gold quality
superior frontal gyrus	UBERON:0002661	67.13	gold quality
granulocyte	CL:0000094	66.86	gold quality
prostate gland	UBERON:0002367	66.66	gold quality
cortex of kidney	UBERON:0001225	66.65	gold quality
popliteal artery	UBERON:0002250	66.43	gold quality
tibial artery	UBERON:0007610	66.34	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	66.06	gold quality
right ovary	UBERON:0002118	65.72	gold quality
pancreas	UBERON:0001264	65.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.24

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.