FAM27C

Summary

FAM27C (family with sequence similarity 27 member C, HGNC:23668) is a long non-coding RNA gene on chromosome 9q13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:23668
Approved symbol	FAM27C
Name	family with sequence similarity 27 member C
Location	9q13
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA374M1.5, FAM27A3, bA7G23.5, FAM27A1
Ensembl gene	ENSG00000231527
Ensembl biotype	lncRNA
Entrez	100132948
RNAcentral	URS00007599C7 — lncRNA, 703 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 75 — 74 lncRNA, 1 retained_intron

ENST00000377542, ENST00000399894, ENST00000417850, ENST00000421848, ENST00000439760, ENST00000443347, ENST00000612999, ENST00000650759, ENST00000651201, ENST00000651393, ENST00000651799, ENST00000653087, ENST00000653460, ENST00000653988, ENST00000655025, ENST00000655049, ENST00000656580, ENST00000656926, ENST00000657353, ENST00000659299, ENST00000660875, ENST00000662964, ENST00000668789, ENST00000669747, ENST00000669872, ENST00000670686, ENST00000671566, ENST00000722356, ENST00000722357, ENST00000722358, ENST00000722359, ENST00000722360, ENST00000722361, ENST00000722362, ENST00000722363, ENST00000722364, ENST00000722365, ENST00000722366, ENST00000722367, ENST00000722368, ENST00000722369, ENST00000722370, ENST00000722371, ENST00000722372, ENST00000722373, ENST00000722374, ENST00000722375, ENST00000722376, ENST00000722377, ENST00000722378, ENST00000722379, ENST00000722380, ENST00000722381, ENST00000722382, ENST00000722383, ENST00000722384, ENST00000722385, ENST00000722386, ENST00000722387, ENST00000722388, ENST00000722389, ENST00000722390, ENST00000722391, ENST00000722392, ENST00000722393, ENST00000722394, ENST00000722395, ENST00000722396, ENST00000722397, ENST00000722398, ENST00000722399, ENST00000722400, ENST00000722401, ENST00000722402, ENST00000722614

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000377542 — 2 exons

Exon	Start	End
ENSE00004042963	61854931	61855371
ENSE00004042979	61854038	61854376

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 93.31.

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	93.31	gold quality
right testis	UBERON:0004534	92.72	gold quality
right uterine tube	UBERON:0001302	92.41	gold quality
testis	UBERON:0000473	91.33	gold quality
adenohypophysis	UBERON:0002196	88.15	gold quality
ventricular zone	UBERON:0003053	86.73	gold quality
pituitary gland	UBERON:0000007	86.35	gold quality
sural nerve	UBERON:0015488	86.08	gold quality
nucleus accumbens	UBERON:0001882	85.33	gold quality
superior frontal gyrus	UBERON:0002661	84.67	gold quality
cerebellum	UBERON:0002037	84.21	gold quality
cerebellar cortex	UBERON:0002129	84.17	gold quality
cerebellar hemisphere	UBERON:0002245	84.10	gold quality
right hemisphere of cerebellum	UBERON:0014890	84.06	gold quality
cortical plate	UBERON:0005343	83.58	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	83.49	gold quality
spleen	UBERON:0002106	83.27	gold quality
hypothalamus	UBERON:0001898	83.25	gold quality
adult mammalian kidney	UBERON:0000082	83.22	gold quality
body of pancreas	UBERON:0001150	83.15	gold quality
kidney	UBERON:0002113	82.89	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	82.78	gold quality
anterior cingulate cortex	UBERON:0009835	82.73	gold quality
caudate nucleus	UBERON:0001873	82.70	gold quality
brain	UBERON:0000955	82.59	gold quality
colonic epithelium	UBERON:0000397	82.36	gold quality
Ammon’s horn	UBERON:0001954	82.28	gold quality
putamen	UBERON:0001874	82.00	gold quality
Brodmann (1909) area 9	UBERON:0013540	81.98	gold quality
ganglionic eminence	UBERON:0004023	81.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	6.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.